Synthetic Studies toward the Myrioneuron Alkaloids

The Myrioneuron alkaloids are a relatively small family of plant-derived alkaloids that present an intriguing array of structural intricacy and biological properties. As such, these natural products have drawn interest from the synthetic community, resulting in creative total syntheses of several family members. This review showcases recent synthetic efforts towards these polycyclic alkaloids. 1 Introduction 1.1 Biological Activity 1.2 Proposed Biosynthesis 2 Synthetic Studies toward the Myrioneuron Alkaloids 2.1 Total Synthesis of Myrioxazines A and B 2.2 Total Synthesis of Myrionine, Myrionidine, and Schoberine 2.3 Total Synthesis of Myrifabrals A and B 2.4 Total Synthesis of Myrioneurinol 3 Conclusions and Outlook