Chronic kidney disease-associated pruritus: what is known and its application in children

被引：1
作者：
Shah, Shweta [1 ,2 ]
Onugha, Elizabeth [1 ,2 ]
Swartz, Sarah J. [1 ,2 ]
机构：
[1] Texas Childrens Hosp, Houston, TX 77030 USA
[2] Baylor Coll Med, Houston, TX 77030 USA
来源：
PEDIATRIC NEPHROLOGY | 2024年 / 39卷 / 01期
关键词：
Pruritus; Kidney failure; Peritoneal dialysis; Hemodialysis; Visual analog scale; UREMIC PRURITUS; DOUBLE-BLIND; HEMODIALYSIS-PATIENTS; PARATHYROID-HORMONE; PLASMA HISTAMINE; CROMOLYN SODIUM; SKIN; MANAGEMENT; OUTCOMES; ITCH;
D O I：
10.1007/s00467-023-05998-8
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Chronic kidney disease-associated pruritus (CKD-aP) or uremic pruritus (UP) is a frequent symptom in patients with kidney failure receiving kidney replacement therapy. Severe chronic kidney disease-associated pruritus correlates with poor outcome in patients on dialysis. It is multifactorial in etiology and has a significant impact on quality of life. There is, however, limited data for children. This review summarizes current epidemiology, clinical characteristics, pruritus scoring systems, and available therapeutic options for pruritus in patients with chronic kidney disease and those receiving dialysis. Optimal care requires proper awareness of the severity of symptoms, the impact on quality of life, and the possible long-term outcomes. Optimizing dialysis prescription and correcting electrolyte abnormalities are important treatment targets. A wide range of therapeutic options is also available although none are well-studied in children. An earlier recognition of this debilitating symptom in children and treatment is imperative.
引用
收藏
页码：25 / 35
页数：11
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