Phenylpropanoids from Solanum capsicoides and their anti-inflammatory activity

被引：3

作者：

Wang, Han ^{[1
]}

Liu, Yan ^{[1
]}

Jang, Yi-Kai ^{[1
]}

Wang, Si-Yi ^{[1
]}

Li, Xiao-Mao ^{[1
]}

Pan, Juan ^{[1
]}

Guan, Wei ^{[1
]}

Algradi, Adnan Mohammed ^{[1
]}

Kuang, Hai-Xue ^{[1
]}

Yang, Bing-You ^{[1
]}

机构：

[1] Heilongjiang Univ Chinese Med, Key Lab Basic & Applicat Res Beiyao, Minist Educ, Harbin 150040, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2023年 / 25卷 / 02期

关键词：

Solanaceae; phenylpropanoids; Solanum capsicoides; spectroscopic methods; anti-inflammatory; CONSTITUENTS; GLYCOSIDES; ROOTS;

D O I：

10.1080/10286020.2022.2066529

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new phenylpropanoids, 4-O-(1''-O-cis-caffeoyl)-beta-glucopyran osyl-1-allyl-3-methoxy-benzene (1), 4'-O-(1''-O-cis-caffeoyl)-beta-glucopyranosyl-hydroxymegastigm-4-en-3-one (2), together with nine known compounds were obtained from the leaves of Solanum capsicoides. Their structures were elucidated based on spectroscopic methods, and comparing spectral data with those in literature. Meanwhile, their anti-inflammatory activities were evaluated on (LPS)-induced RAW 246.7 cells, and 1, 9, and 10 showed better inhibitory effects with IC50 values of 17.19 +/- 1.12, 18.15 +/- 0.47, and 19.8 +/- 0.95 mu M, respectively.

引用

页码：118 / 124

页数：7

共 23 条

[1]

Buske A, 2001, EUR J ORG CHEM, V2001, P3537, DOI 10.1002/1099-0690(200109)2001:18<3537::AID-EJOC3537>3.0.CO

[2]

2-A

[3] Constituents of Cydonia vulgaris: Isolation and structure elucidation of four new flavonol glycosides and nine new alpha-ionol-derived glycosides [J].

DeTommasi, N ;

Piacente, S ;

DeSimone, F ;

Pizza, C .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1996, 44 (07) :1676-1681

[4]

Hiroyuki, 1982, CHEM PHARM BULL, V30, P4554

[5]

Kim Chung Sub, 2014, Natural Product Sciences, V20, P86

[6] Tribulusamide A and B, new hepatoprotective lignanamides from the fruits of Tribulus terrestris: Indications of cytoprotective activity in murine hepatocyte culture [J].

Li, JX ;

Shi, Q ;

Xiong, QB ;

Prasain, JK ;

Tezuka, Y ;

Hareyama, T ;

Wang, ZT ;

Tanaka, K ;

Namba, T ;

Kadota, S .

PLANTA MEDICA, 1998, 64 (07) :628-631

[7]

Li X.Y., 2008, NAT PROD RES DEV, V20

[8]

Li Z., 1988, SHANGHAI YIKE DAXUE, V15, P68

[9]

Liu, 2013, MIL MED, V37, P130

[10] A New Phenylpropanoid from the Roots of Solanum melongena L. and Evaluation of Anti-inflammatory Activity [J].

Liu, Yan ;

Yin, Xin ;

Sun, Yanping ;

Liu, Yuan ;

Lu, Dongxv ;

Zhou, Yuanyuan ;

Adnan, Mohammed Algradi ;

Pan, Juan ;

Guan, Wei ;

Yang, Bingyou ;

Kuang, Haixue .

RECORDS OF NATURAL PRODUCTS, 2021, 15 (04) :261-266

← 1 2 3 →