Clinical factors associated with extended hospitalization in pediatric patients ≥3 years of age with respiratory syncytial virus or human metapneumovirus infection: A Japanese single-center, retrospective study

被引：0

作者：

Hayashida, Shingo ^{[1
]}

Nagano, Nobuhiko ^{[1
]}

Morohashi, Tamaki ^{[1
]}

Momoki, Emiko ^{[1
]}

Nezu, Keiko ^{[1
]}

Shimozawa, Katsuyoshi ^{[1
]}

Ishii, Wakako ^{[1
]}

Okahashi, Aya ^{[1
]}

Morioka, Ichiro ^{[1
]}

机构：

[1] Nihon Univ, Dept Pediat & Child Hlth, Sch Med, 30-1,Oyaguchi,Kami cho,Itabashi ku, Tokyo 1738610, Japan

来源：

MEDICINE | 2023年 / 102卷 / 42期

关键词：

antibiotics; clinical risk factor; co-bacterial colonization; hospitalization; pediatric patient; underlying disease; YOUNG-CHILDREN; RISK-FACTORS; DISEASE; BURDEN; SEVERITY; INFANTS;

D O I：

10.1097/MD.0000000000035565

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) infections are common in children worldwide. However, the clinical factors related to extended hospitalization in Japanese patients aged >= 3 years remain elusive. We aimed to elucidate the clinical risk factors contributing to hospital stays >= 7 days in patients with RSV and hMPV infections. Patients >= 3 years of age who were hospitalized due to RSV or hMPV infection between 2014 to 2020 were included. Twenty-one RSV- and 27 hMPV-infected patients were enrolled. Patients were divided into 2 groups: hospitalization for >= and <7 days. Univariate and multivariate analyses determined the clinical risk factors contributing to hospital stay >= 7 days. The RSV- and hMPV-infected patients had similar clinical characteristics. The clinical risk factors contributing to extended hospitalization were analyzed in the 48 infected patients of the 2 groups. The presence of prophylactic antibiotics usage, co-bacterial colonization, and underlying diseases were extracted by univariate analysis (P<.05). In multivariate analysis, underlying diseases were determined as an independent clinical risk factor (odds ratio 8.09, P=.005). Underlying diseases contributed to extended hospitalization in RSV- or hMPV-infected patients >= 3 years of age.

引用

页数：6

共 37 条

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