Colloquium: Positronium physics and biomedical applications

被引：48

作者：

Bass, Steven D. ^{[1
,2
]}

Mariazzi, Sebastiano ^{[3
,4
]}

Moskal, Pawel ^{[2
,5
]}

Stepien, Ewa ^{[2
,5
]}

机构：

[1] Kitzbuhel Ctr Phys, A-6370 Kitzbuhel, Austria

[2] Jagiellonian Univ, Marian Smoluchowski Inst Phys, PL-30348 Krakow, Poland

[3] Univ Trento, Dept Phys, Via Sommar 14, I-38123 Trento, Italy

[4] TIFPA INFN, Via Sommar 14, I-38123 Trento, Italy

[5] Jagiellonian Univ, Ctr Theranost, PL-31034 Krakow, Poland

来源：

REVIEWS OF MODERN PHYSICS | 2023年 / 95卷 / 01期

关键词：

ANNIHILATION LIFETIME SPECTROSCOPY; MONTE-CARLO CALCULATIONS; J-PET; SLOW POSITRONS; IN-FLIGHT; PRECISION-MEASUREMENT; MESOPOROUS MATERIALS; PHASE-TRANSITION; KEV ELECTRON; ENERGY-LOSS;

D O I：

10.1103/RevModPhys.95.021002

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Positronium is the simplest bound state, built of an electron and a positron. Studies of positronium in vacuum and its decays in medium tell us about quantum electrodynamics (QED) and about the structure of matter and biological processes of living organisms at the nanoscale, respectively. Spectroscopic measurements constrain our understanding of QED bound state theory. Searches for rare decays and measurements of the effect of gravitation on positronium are used to look for new physics phenomena. In biological materials positronium decays are sensitive to the intermolecular and intramolecular structure and to the metabolism of living organisms ranging from single cells to human beings. This leads to new ideas of positronium imaging in medicine using the fact that during positron emission tomography (PET) as much as 40% of positron annihilation occurs through the production of positronium atoms inside the patient's body. A new generation of the high sensitivity and multiphoton total-body PET systems opens perspectives for clinical applications of positronium as a biomarker of tissue pathology and the degree of tissue oxidation.

引用

页数：21

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