The clinical effect of Huoxue Huayu Recipe combined with ibuprofen in patients with postoperative pain after ankle fracture

被引:0
|
作者
Zhang, Yaojun [1 ]
Fan, Xiaolin [2 ]
Pang, Kunfang [3 ]
Liu, Deheng [4 ,5 ]
机构
[1] Fushan Dist Peoples Hosp, Dept Trauma Surg, Yantai, Peoples R China
[2] Qingdao Univ, Qingdao Canc Hosp Qingdao, Pain Dept, Qingdao Cent Hosp, Qingdao, Peoples R China
[3] Qingdao Univ, Hiser Med Ctr Qingdao, Qingdao Hiser Hosp, Anesthesia Operating Room, Qingdao, Peoples R China
[4] Shandong Univ, Qilu Hosp Qingdao, Cheeloo Coll Med, Dept Hand & Foot Surg, Qingdao, Shandong, Peoples R China
[5] Shandong Univ, Qilu Hosp Qingdao, Cheeloo Coll Med, Dept Hand & Foot Surg, 758 Hefei Rd, Qingdao 266035, Shandong, Peoples R China
关键词
Fracture; ankle joint; postoperative; Huoxue Huayu Recipe; ibuprofen;
D O I
10.1080/02648725.2023.2200350
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The curative effect of Huoxue Huayu Recipe combined with ibuprofen in the postoperative pain in patients with ankle fractures was analyzed. 68 patients with ankle fractures were divided into study group (n = 34, Huoxue Huayu Decoction combined with ibuprofen) and control group (n = 34, ibuprofen). The levels of inflammatory factors, ankle joint function, VAS score and bone metabolism indexes were compared. Complications, isokinetic muscle strength and clinical related index levels were compared after treatment. High AOFAS score and low VAS score were identified in the study group compared with the control group at 1 week, 1 month and 2 months after operation. Compared to the control group, the incidence of postoperative complications was declined in the study group. After treatment, IL-6 and TNF-a levels in both groups were significantly decreased, and the study group had lower IL-6 and TNF-a levels. After treatment, the torque acceleration energy, relative peak torque value and endurance in the study group were obviously improved. The disappearance time of swelling and pain, fracture healing time, and complete weight-bearing time in the study group were reduced compared to the control group. After treatment, BGP and BALP levels in study group were higher than control group. Huoxue Huayu Recipe combined with ibuprofen can reduce inflammatory factors levels in patients with ankle fracture, improve isokinetic muscle strength and ankle function, and accelerate the recovery of patients.
引用
收藏
页码:2613 / 2627
页数:15
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