Biological properties of bioactive compounds from the fruit and leaves of the genipap tree (Genipa americana L.): A systematic review

被引:7
作者
de Assis, Renata Carmo [1 ]
Monteiro, Gabrielly Rossi [1 ]
Valentim, Ashley Brito [1 ]
Maia, Carla Soraya Costa [1 ]
Felipe, Stela Mirla da Silva [1 ]
Rabelo, Claisa Andrea Freitas [1 ]
Ceccatto, Vania Marilande [1 ]
Alves, Carlucio Roberto [1 ]
机构
[1] Univ Estadual Ceara, Ave Dr Silas Munguba,1700, Campus Itaperi, BR-60714903 Fortaleza, CE, Brazil
关键词
Genipap; Genipa americana L; Bioactive compounds; Iridoids; Antioxidant; We thank Dr; Livia Valquiria Raposo Dickson Chen for granting us the copyright of the figure of the genipap fruit; ANTIOXIDANT ACTIVITY; ANTICOAGULANT; POLYSACCHARIDES; EXTRACTION; SERUM; FOOD;
D O I
10.1016/j.fbio.2023.102514
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Genipa americana L. is widely distributed in diverse phytogeographic domains, from Mexico to Argentina. Pulp, seeds and bark of genipap have biological properties with therapeutic potential for the treatment of several pathologies. The nutritional composition of genipap, the fruit of G. americana L. favors its use for having high contents of bioactive compounds, fibers and vitamins. The aim of this systematic review was to provide an overview of the bioactive compounds of G. americana L. and their effects in human, animal, and in vitro assays. Nine studies met the inclusion criteria, 2 in humans, 4 in animals, and 3 in biological assays. The main results of the review showed that the metabolites excreted in human urine after consumption of genipap juice were iri-doids, medium chain fatty acids and hydroxycinnamic acids. The leaf extract of G. americana L. showed relevant antiplatelet, anticoagulant and antithrombotic activity, besides antioxidant, anticonvulsant and antiparasitic effects. The extracts of genipap seeds and peels showed antioxidant inhibition of acetylcholinesterase and tyrosinase. The extract of the fruit pulp showed high inhibitory enzymatic activity alpha-glucosidase, alpha-amylase, lipase and antiglycation activity, anti-diabetic potential. It was concluded that the biological properties of the fruit and its fractions show benefits of its consumption and possibilities for the development of new products.
引用
收藏
页数:13
相关论文
共 92 条
[11]   Multiple Biological Effects of an Iridoid Glucoside, Catalpol, and Its Underlying Molecular Mechanisms [J].
Bhattamisra, Subrat Kumar ;
Yap, Kah Heng ;
Rao, Vikram ;
Choudhury, Hira .
BIOMOLECULES, 2020, 10 (01)
[12]  
Bonnet A., 2015, COMUNICADO TE CNI CO
[13]  
Brasil Ministerio do Meio Ambiente, 2023, BIOD MMA LANC LIVR E
[14]  
Brasil Ministerio do Meio Ambiente Secretaria de Biodiversidade, 2018, ESP NAT FLOR BRAS VA
[15]   The Kallikrein Inhibitor from Bauhinia bauhinioides (BbKI) shows antithrombotic properties in venous and arterial thrombosis models [J].
Brito, Marlon V. ;
de Oliveira, Cleide ;
Salu, Bruno R. ;
Andrade, Sonia A. ;
Malloy, Paula M. D. ;
Sato, Ana C. ;
Vicente, Cristina P. ;
Sampaio, Misako U. ;
Maffei, Francisco H. A. ;
Oliva, Maria Luiza V. .
THROMBOSIS RESEARCH, 2014, 133 (05) :945-951
[16]   Analytical Methods for Determining Bioavailability and Bioaccessibility of Bioactive Compounds from Fruits and Vegetables: A Review [J].
Carbonell-Capella, Juana M. ;
Buniowska, Magdalena ;
Barba, Francisco J. ;
Esteve, Maria J. ;
Frigola, Ana .
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, 2014, 13 (02) :155-171
[17]  
Castro L. L. D. D., 2019, CIENC ANIM BRAS, V20, DOI 10.
[18]  
Cozzolino S. M. F., 2020, BIODISPONIBILIDADE N, V6a
[19]   The antioxidant and antiglycation activities of selected spices and other edible plant materials and their decay in sugar-protein systems under thermal stress [J].
Cristian Favre, Leonardo ;
Paula Lopez-Fernandez, Maria ;
dos Santos Ferreira, Cristina ;
Florencia Mazzobre, Maria ;
Mshicileli, Ndumiso ;
van Wyk, Jessy ;
del Pilar Buera, Maria .
FOOD CHEMISTRY, 2022, 371
[20]   Trypanocidal activity of polysaccharide extract from Genipa americana leaves [J].
da Silva Souza, Racquel Oliveira ;
Sousa, Paloma Ledo ;
Pessoa Bezerra de Menezes, Ramon Roseo Paula ;
Sampaio, Tiago Lima ;
Tessarolo, Louise Donadello ;
Oliveira Silva, Francisca Crislandia ;
Pereira, Maria Goncalves ;
Costa Martins, Alice Maria .
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 210 :311-317