Investigating the trans-membrane transport of HAIYPRH peptide-decorated nano-drugs

被引：0

作者：

Zhang, Xiaowan ^{[1
]}

Shan, Meirong ^{[1
]}

Li, Siying ^{[1
]}

Zhao, Jing ^{[1
]}

Pang, Xuelei ^{[1
]}

Yang, Guocheng ^{[1
]}

Shan, Yuping ^{[1
]}

机构：

[1] Changchun Univ Technol, Adv Inst Mat Sci, Sch Chem & Life Sci, Changchun 130012, Peoples R China

来源：

PHYSICAL CHEMISTRY CHEMICAL PHYSICS | 2023年 / 25卷 / 14期

基金：

中国国家自然科学基金;

关键词：

DELIVERY; NANOPARTICLES; GLIOMA;

D O I：

10.1039/d3cp00342f

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Transferrin (Tf) has been effectively used to promote the cellular uptake of HAIYPRH (T7) peptide-conjugated nano-drugs. In this study, the enhancing effect of Tf on T7-decorated nano-drug transport was investigated using force tracing and nano-indentation techniques at a single-particle/cell level. Furthermore, the results were confirmed by ensemble fluorescence imaging.

引用

页码：9766 / 9771

页数：6