Investigating the trans-membrane transport of HAIYPRH peptide-decorated nano-drugs

被引:0
|
作者
Zhang, Xiaowan [1 ]
Shan, Meirong [1 ]
Li, Siying [1 ]
Zhao, Jing [1 ]
Pang, Xuelei [1 ]
Yang, Guocheng [1 ]
Shan, Yuping [1 ]
机构
[1] Changchun Univ Technol, Adv Inst Mat Sci, Sch Chem & Life Sci, Changchun 130012, Peoples R China
基金
中国国家自然科学基金;
关键词
DELIVERY; NANOPARTICLES; GLIOMA;
D O I
10.1039/d3cp00342f
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Transferrin (Tf) has been effectively used to promote the cellular uptake of HAIYPRH (T7) peptide-conjugated nano-drugs. In this study, the enhancing effect of Tf on T7-decorated nano-drug transport was investigated using force tracing and nano-indentation techniques at a single-particle/cell level. Furthermore, the results were confirmed by ensemble fluorescence imaging.
引用
收藏
页码:9766 / 9771
页数:6
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