The relationship of prognostic nutritional index with prognosis and inflammation in patient with heart failure and reduced ejection fraction

被引:3
作者
Davran, Gul Busra [1 ]
Davran, Ahmet Cetin [2 ]
Karabag, Turgut [3 ]
机构
[1] Karamanoglu Mehmet Bey Univ, Dept Therapy & Rehabil, Phsiotherapy Program, Karaman, Turkey
[2] Saglik Bilimleri Univ, Istanbul Educ & Res Hosp, Dept Coronary Care Unit, Istanbul, Turkey
[3] Saglik Bilimleri Univ, Istanbul Educ & Res Hosp, Dept Cardiol, Istanbul, Turkey
关键词
Heart failure; prognostic nutritional index; prognosis; inflammation; RISK; MALNUTRITION; MORBIDITY; MORTALITY; SURGERY;
D O I
10.1177/02601060221103017
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Background: Malnutrition is closely associated with heart failure, and known to be closely associated with mortality and morbidity in these patients. Aims: We investigated the relationship of the prognostic nutritional index (PNI), which is a criterion of nutritional status in patients with heart failure with reduced ejection fraction (HFrEF), with prognosis and parameters indicating inflammation. Methods: 139 patients admitted to the coronary intensive care unit with symptoms of decompensated congestive heart failure were included to the study. Patients were with heart failure with ejection fraction <%40 and decompensated for any reason. Patients who died within 1 year in hospital or follow-up were considered to have reached the endpoint. Groups were divided into 2 groups as Group 1, the exitus; (23 patients, 7 M, mean age; 69.2 +/- 15.0 years) and group 2, the non-exitus; (116 patients, 57 M, mean age; 69.3 +/- 11.5 years). PNI was calculated with the formula ALB(g/L) + 5 x Total lymphocyte count(10(9)/L). Results: PNI was significantly lower in group 1. Neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and systemic inflamatory index values were significantly higher in group 1. PNI was significantly associated with these parameters. Conclusion: Low PNI scores in HFrEF patients may be associated with a worse prognosis and hematological parameters indicating more negative inflammation. PNI was found to be an independent predictor of mortality.
引用
收藏
页码:737 / 743
页数:7
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