Factors affecting hesitancy toward COVID-19 vaccine booster doses in Canada: a cross-national survey

被引：2

作者：

Leigh, Jeanna Parsons ^{[1
,2
,3
,4
]}

FitzGerald, Emily A. ^{[1
]}

Moss, Stephana J. ^{[1
,5
]}

Brundin-Mather, Rebecca ^{[6
]}

Dodds, Alexandra ^{[1
]}

Stelfox, Henry T. ^{[6
,7
]}

Dube, Eve ^{[8
,9
]}

Fiest, Kirsten M. ^{[6
,7
,10
,11
]}

Halperin, Donna ^{[3
,4
,12
]}

Ahmed, Sofia B. ^{[7
,13
,14
]}

MacDonald, Shannon E. ^{[15
,16
]}

Straus, Sharon E. ^{[17
,18
,19
]}

Manca, Terra ^{[16
,20
]}

Kamstra, Josh Ng ^{[21
,22
]}

Soo, Andrea ^{[6
,23
]}

Longmore, Shelly ^{[6
]}

Kupsch, Shelly ^{[6
]}

Sept, Bonnie ^{[6
]}

Halperin, Scott ^{[3
,4
,24
,25
]}

机构：

[1] Dalhousie Univ, Fac Hlth, Sch Hlth Adm, Halifax, NS, Canada

[2] Dalhousie Univ, Dept Crit Care Med, Halifax, NS, Canada

[3] Canadian Ctr Vaccinol, Halifax, NS, Canada

[4] IWK Hlth Ctr, Halifax, NS, Canada

[5] Univ Pittsburgh, CRISMA Ctr, Dept Crit Care Med, Pittsburgh, PA USA

[6] Univ Calgary, Dept Crit Care Med, Calgary, AB, Canada

[7] Univ Calgary, OBrien Inst Publ Hlth, Calgary, AB, Canada

[8] Univ Laval, Ctr Rech CHU Quebec, Quebec City, PQ, Canada

[9] Inst Natl Sante Publ Quebec, Quebec City, PQ, Canada

[10] Univ Calgary, Cumming Sch Med, Dept Psychiat, Calgary, AB, Canada

[11] Univ Calgary, Hotchkiss Brain Inst, Cumming Sch Med, Calgary, AB, Canada

[12] St Francis Xavier Univ, Rankin Sch Nursing, Antigonish, NS, Canada

[13] Univ Calgary, Dept Med, Calgary, AB, Canada

[14] Univ Calgary, Libin Cardiovasc Inst, Calgary, AB, Canada

[15] Univ Alberta, Sch Publ Hlth, Edmonton, AB, Canada

[16] Univ Alberta, Fac Nursing, Edmonton, AB, Canada

[17] Unity Hlth Toronto, St Michaels Hosp, Li Ka Shing Knowledge Inst, Toronto, ON, Canada

[18] Univ Toronto, Dept Med, Toronto, ON, Canada

[19] Univ Toronto, Inst Hlth Policy Management & Evaluat, Toronto, ON, Canada

[20] Dalhousie Univ, Sociol & Social Anthropol, Halifax, NS, Canada

[21] Univ Hawaii Manoa, John A Burns Sch Med, Dept Surg, Honolulu, HI 96813 USA

[22] Queens Med Ctr, Dept Surg, Honolulu, HI USA

[23] Alberta Hlth Serv, Calgary, AB, Canada

[24] Dalhousie Univ, Fac Med, Dept Pediat, Halifax, NS, Canada

[25] Dalhousie Univ, Fac Med, Dept Microbiol & Immunol, Halifax, NS, Canada

来源：

CANADIAN JOURNAL OF PUBLIC HEALTH-REVUE CANADIENNE DE SANTE PUBLIQUE | 2024年 / 115卷 / 01期

基金：

加拿大健康研究院;

关键词：

Vaccine hesitancy; Vaccination; COVID-19; SARS-CoV-2; Survey; Questionnaire; Hesitation a la vaccination; vaccination; SRAS-CoV-2; enquete; questionnaire;

D O I：

10.17269/s41997-023-00823-z

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

ObjectiveCOVID-19 transmission, emergence of variants of concern, and weakened immunity have led to recommended vaccine booster doses for COVID-19. Vaccine hesitancy challenges broad immunization coverage. We deployed a cross-national survey to investigate knowledge, beliefs, and behaviours toward continued COVID-19 vaccination.MethodsWe administered a national, cross-sectional online survey among adults in Canada between March 16 and March 26, 2022. We utilized descriptive statistics to summarize our sample, and tested for demographic differences, perceptions of vaccine effectiveness, recommended doses, and trust in decisions, using the Rao-Scott correction for weighted chi-squared tests. Multivariable logistic regression was adjusted for relevant covariates to identify sociodemographic factors and beliefs associated with vaccine hesitancy.ResultsWe collected 2202 completed questionnaires. Lower education status (high school: odds ratio (OR) 1.90, 95% confidence interval (CI) 1.29, 2.81) and having children (OR 1.89, CI 1.39, 2.57) were associated with increased odds of experiencing hesitancy toward a booster dose, while higher income ($100,000-$149,999: OR 0.60, CI 0.39, 0.91; $150,000 or more: OR 0.49, CI 0.29, 0.82) was associated with decreased odds. Disbelief in vaccine effectiveness (against infection: OR 3.69, CI 1.98, 6.90; serious illness: OR 3.15, CI 1.69, 5.86), disagreeing with government decision-making (somewhat disagree: OR 2.70, CI 1.38, 5.29; strongly disagree: OR 4.62, CI 2.20, 9.7), and beliefs in over-vaccinating (OR 2.07, CI 1.53, 2.80) were found associated with booster dose hesitancy.ConclusionCOVID-19 vaccine hesitancy may develop or increase regarding subsequent vaccines. Our findings indicate factors to consider when targeting vaccine-hesitant populations. ObjectifLa transmission de la COVID-19, l'emergence de variants preoccupants et l'affaiblissement de l'immunite ont conduit a recommander des doses de rappel de vaccin contre la COVID-19. L'hesitation a la vaccination remet en question une large couverture vaccinale. Nous avons deploye une enquete transnationale pour etudier les connaissances, les croyances et les comportements en faveur de la poursuite de la vaccination contre la COVID-19.MethodesNous avons mene une enquete nationale transversale en ligne aupres d'adultes au Canada, entre le 16 et le 26 mars 2022. Nous avons utilise des statistiques descriptives pour resumer notre echantillon et teste les differences demographiques, les perceptions de l'efficacite des vaccins, les doses recommandees et la confiance dans les decisions, en utilisant la correction de Rao-Scott pour les tests du chi carre ponderes. La regression logistique multivariee a ete ajustee pour les covariables pertinentes afin d'identifier les facteurs sociodemographiques et les croyances associes a l'hesitation a la vaccination.ResultatsNous avons collecte 2 202 questionnaires remplis. Un faible niveau d'education (lycee : rapport de cotes (OR) 1,90, intervalle de confiance (IC) a 95% 1,29, 2,81) et le fait d'avoir des enfants (OR 1,89, IC 1,39, 2,57) etaient associes a une probabilite accrue d'eprouver une hesitation a l'egard d'une dose de rappel, tandis qu'un revenu plus eleve (100 000 $-149 999 $ : OR 0,60, IC 0,39, 0,91; 150 000 $ ou plus : OR 0,49, IC 0,29, 0,82) etait associe a une diminution des probabilites. Incredulite dans l'efficacite du vaccin (contre l'infection : OR 3,69, IC 1,98, 6,90; maladie grave : OR 3,15, IC 1,69, 5,86), en desaccord avec la prise de decision du gouvernement (plutot en desaccord : OR 2,70, IC 1,38, 5,29; fortement en desaccord : OR 4,62, IC 2,20, 9,7) et la croyance dans le sur-vaccination (OR 2,07, IC 1,53, 2,80) ont ete associees a une hesitation a recevoir une dose de rappel.ConclusionUne hesitation a l'egard du vaccin contre la COVID-19 peut se developper ou augmenter a l'egard des vaccins ulterieurs. Nos resultats indiquent des facteurs a prendre en compte lors du ciblage des populations hesitantes a la vaccination.

引用

页码：26 / 39

页数：14

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