Perioperative Clinical Features and Long-term Prognosis After Oblique Lateral Interbody Fusion (OLIF), OLIF With Anterolateral Screw Fixation, or OLIF With Percutaneous Pedicle Fixation: A Comprehensive Treatment Strategy for Patients With Lumbar Degenerative Disease

Objective: To compare the efficacy of oblique lateral interbody fusion (OLIF), OLIF com-bined with anterolateral screw fixation (OLIF-AF), and OLIF combined with percutaneous pedicle screw fixation (OLIF-PF) in the treatment of single-level or 2-level degenerative lumbar disease. Methods: Between January 2017 and 2021, 71 patients were treated with OLIF and com-bined OLIF. The demographic data, clinical outcomes, radiographic outcomes, and com-plications were compared among the 3 groups. Results: The operative time and intraoperative blood loss in the OLIF (p < 0.05) and OLIF-AF (p < 0.05) groups were lower than in the OLIF-PF group. Posterior disk height improve-ment in the OLIF-PF group was better than in the OLIF (p < 0.05) and OLIF-AF (p < 0.05) groups. In terms of foraminal height (FH), the OLIF-PF group was significantly better than the OLIF group (p < 0.05), but there was no significant difference between the OLIF-PF and OLIF-AF groups (p > 0.05) or between the OLIF and OLIF-AF groups (p > 0.05). There were no significant differences in fusion rates, the incidence of complications, lumbar lordo-sis, anterior disc height, and cross-sectional area among the 3 groups (p > 0.05). The OLIF-PF group had significantly lower rates of subsidence than the OLIF group (p < 0.05). Conclusion: OLIF remains a viable option with similar patient-reported outcomes and fu-sion rates compared with surgeries that include lateral and posterior internal fixation while greatly reducing the financial burden, intraoperative time, and intraoperative blood loss. OLIF has a higher subsidence rate than lateral and posterior internal fixation, but most sub-sidence is mild and has no adverse effect on clinical and radiographic outcomes.