Self-assembled polylactic acid (PLA): Synthesis, properties and biomedical applications

被引：21

作者：

Chen, Tianyu ^{[1
]}

Zhao, Xiaoying ^{[1
]}

Weng, Yunxuan ^{[2
]}

机构：

[1] Beijing Technol & Business Univ, Coll Chem & Mat Engn, Beijing, Peoples R China

[2] Beijing Technol & Business Univ, Beijing Key Lab Qual Evaluat Technol Hyg & Safety, Beijing, Peoples R China

来源：

FRONTIERS IN CHEMISTRY | 2023年 / 10卷

基金：

中国国家自然科学基金;

关键词：

self-assembly; polylactic acid; surface microstructure; surface topography; biomaterials; INDUCED PHASE-SEPARATION; BREATH-FIGURE; POLY(LACTIC ACID); DRUG-DELIVERY; POLYMER-FILMS; CRYSTALLIZATION; NANOPARTICLES; MEMBRANE; SCAFFOLD; FOAMS;

D O I：

10.3389/fchem.2022.1107620

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The surface morphology and topography of cell culture substrates play an important role in cell proliferation and growth. Regulation of the surface microstructure allows the development of tissue culture media suitable for different cells. Polylactic acid (PLA) is a biobased and biodegradable (under defined conditions) polymer with low immunogenicity, non-toxicity, and good mechanical properties, which have facilitated their pharmaceutical and biomedical applications. This review summarizes recent advances in the synthesis and self-assembly of surface microstructure based on PLA materials and discusses their biomedical applications such as cell culturing and tissue engineering.

引用

页数：8

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