Safety of coronavirus disease 2019 vaccines in 213 adult patients with sickle cell disease

被引：5

作者：

Joseph, Laure ^{[1
,2
]}

Corbasson, Anne ^{[3
]}

Manceau, Sandra ^{[1
,2
]}

Khimoud, Djamal ^{[3
]}

Meunier, Benoit ^{[1
]}

Cheminet, Geoffrey ^{[3
,4
]}

Lefrere, Francois ^{[1
]}

Jannot, Anne-Sophie ^{[4
,5
]}

Lu, Estelle ^{[5
]}

Arlet, Jean-Benoit ^{[2
,3
,4
,6
]}

机构：

[1] Hop Necker Enfants Malad, AP HP, Dept Biotherapy, French Natl Sickle Cell Dis Referral Ctr, Paris, France

[2] Lab Excellence Sur Globule Rouge GR Ex, Paris, France

[3] Hop Europeen Georges Pompidou, AP HP, Internal Med Dept, French Natl Sickle Cell Dis Referral Ctr, Paris, France

[4] Univ Paris Cite, Fac Med, Paris, France

[5] Hop Europeen Georges Pompidou, AP HP, Dept Med Informat Biostat & Publ Hlth, Paris, France

[6] Hop Necker Enfants Malad, AP HP, INSERM, U1163,CNRS 8254,Inst IMAGINE, Paris, France

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2023年 / 200卷 / 05期

关键词：

coronavirus disease 2019 vaccine; hospital admission; safety; sickle cell disease; vaccination; INACTIVATED INFLUENZA VACCINE;

D O I：

10.1111/bjh.18547

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Given the lack of information about safety of the COVID-19 vaccines for sickle cell disease (SCD) patients, we sought to determine whether COVID-19 vaccine was associated with subsequent hospital admission for vaso-occlusive events (VOEs). We included 402 patients with SCD, including 88 regularly transfused. As of July 31, 2021, 213 (53.0%) of them had received a least one dose of COVID vaccine (Pfizer 93.0%). We showed similar risk of hospital admission for a VOE among vaccinated patients (whether transfused or not) and among a control group of non-vaccinated patients matched for age, sex and genotype.

引用

页码：563 / 567

页数：5

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