Evaluation of inherent properties of the carboxymethyl cellulose (CMC) for potential application in tissue engineering focusing on bone regeneration

被引：10

作者：

Mehrabi, Arezou ^{[1
,2
]}

Jalise, Saeedeh Zare ^{[3
]}

Hivechi, Ahmad ^{[2
]}

Habibi, Sina ^{[4
]}

Kebria, Maziar Malekzadeh ^{[1
,2
]}

Haramshahi, Mohammad Amin ^{[1
,2
]}

Latifi, Noorahmad ^{[5
]}

Karimi, Afzal ^{[2
,6
]}

Milan, Peiman Brouki ^{[1
,2
]}

机构：

[1] Iran Univ Med Sci, Fac Adv Technol Med, Dept Tissue Engn & Regenerat Med, Tehran, Iran

[2] Iran Univ Med Sci, Cellular & Mol Res Ctr, Tehran, Iran

[3] Qom Univ Med Sci, Sch Med, Dept Tissue Engn & Appl Cell Sci, Qom, Iran

[4] Iran Univ Med Sci, Fac Allied Med, Dept Med Lab Sci, Tehran, Iran

[5] Iran Univ Med Sci, Hazrat Fatemeh Hosp, Dept Plast & Reconstruct Surg, Tehran, Iran

[6] Iran Univ Med Sci, Fac Adv Technol Med, Tehran, Iran

来源：

POLYMERS FOR ADVANCED TECHNOLOGIES | 2024年 / 35卷 / 01期

关键词：

biomedical; bone; carboxymethyl cellulose; tissue engineering; POLYELECTROLYTE COMPLEX SCAFFOLDS; NANOCELLULOSE-BASED HYDROGELS; CHITOSAN-BASED SCAFFOLDS; CROSS-LINKING; MICROCRYSTALLINE CELLULOSE; BACTERIAL CELLULOSE; IN-VITRO; POLYVINYL-ALCOHOL; HYALURONIC-ACID; GRAPHENE OXIDE;

D O I：

10.1002/pat.6258

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Biomaterials are essential in medicine because these biological macromolecules have appropriately replaced classical tissue grafting techniques for their valuable features. Bone tissue engineering has persistently developed since "tissue engineering" was suggested. Carboxymethyl cellulose (CMC) is the first FDA-approved water-soluble derivative of cellulose that could be targeted for desired bone tissue graft. Numerous studies on CMC as a component created for bone tissue have recently been published. Because of its carboxylate groups, CMC is hydrophilic. CMC can crosslink with varied materials, such as synthetic and natural polymers, enabling innovative bone structure biomaterials. These carboxylate groups are responsible for in situ gelations and bio-adhesion characteristics. In this review, the current progress and inherent characteristics of CMC-based bone scaffold materials are discussed.

引用

页数：18