Construction of unsymmetrical heterobiaryls via the Cp*Rh(iii)-catalysed C-H/C-H coupling of heteroarenes

被引：6

作者：

Parmar, Diksha ^{[1
,2
]}

Sharma, Tamanna ^{[1
]}

Sharma, Akhilesh K. K. ^{[3
]}

Sharma, Upendra ^{[1
,2
]}

机构：

[1] CSIR IHBT, Chem Technol Div, C H Activat & Phytochemistry Lab, Palampur 176061, India

[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India

[3] Barcelona Inst Sci & Technol, Inst Chem Res Catalonia ICIQ CERCA, Ave Paisos Catalans,16, Tarragona 43007, Spain

来源：

CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 63期

关键词：

QUINOLINE N-OXIDES; FUNCTIONALIZATION; ACTIVATION; MECHANISM; INDOLES; ALKYNES; RHODIUM; ACCESS; AZOLES; BONDS;

D O I：

10.1039/d3cc03166g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, a concise method for the Rh(iii)-catalyzed, directing-group-assisted C-H/C-H cross-coupling of N-heterocycles (quinolines, indolines, indoles, pyridines, pyrimidines, pyrazoles) with other heteroarenes (benzoxazoles, benzofurans, and thiophenes) is disclosed for the synthesis of unsymmetrical heterobiaryl compounds in good to excellent yields. A plausible catalytic cycle has been delineated based on experimental and computational mechanistic studies.

引用

页码：9646 / 9649

页数：4

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