Construction of unsymmetrical heterobiaryls via the Cp*Rh(iii)-catalysed C-H/C-H coupling of heteroarenes

被引：6
|
作者：
Parmar, Diksha [1 ,2 ]
Sharma, Tamanna [1 ]
Sharma, Akhilesh K. K. [3 ]
Sharma, Upendra [1 ,2 ]
机构：
[1] CSIR IHBT, Chem Technol Div, C H Activat & Phytochemistry Lab, Palampur 176061, India
[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
[3] Barcelona Inst Sci & Technol, Inst Chem Res Catalonia ICIQ CERCA, Ave Paisos Catalans,16, Tarragona 43007, Spain
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 63期
关键词：
QUINOLINE N-OXIDES; FUNCTIONALIZATION; ACTIVATION; MECHANISM; INDOLES; ALKYNES; RHODIUM; ACCESS; AZOLES; BONDS;
D O I：
10.1039/d3cc03166g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, a concise method for the Rh(iii)-catalyzed, directing-group-assisted C-H/C-H cross-coupling of N-heterocycles (quinolines, indolines, indoles, pyridines, pyrimidines, pyrazoles) with other heteroarenes (benzoxazoles, benzofurans, and thiophenes) is disclosed for the synthesis of unsymmetrical heterobiaryl compounds in good to excellent yields. A plausible catalytic cycle has been delineated based on experimental and computational mechanistic studies.
引用
收藏
页码：9646 / 9649
页数：4
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