H3.3-K27M neoantigen vaccine elicits CD4+ and CD8+ T cells immunity and improved prognosis against diffuse intrinsic pontine glioma

被引：1
|
作者：
Zhang, Yang
Ji, Nan
Chen, Gang
Wu, Haiyang
Wang, Yi
Li, Xiao'ou
Xu, Wei
Peng, Ling
Li, Tian
Wang, Yi
Zhang, Li-Feng
Sun, Shengjun
Zhao, Xiaobing
Li, Si
Alexander, Peter
Zhang, Liwei
Li, Qi-Jing
机构：
来源：
CANCER RESEARCH | 2023年 / 83卷 / 08期
关键词：
D O I：
10.1158/1538-7445.AM2023-CT086
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
CT086
引用
收藏
页数：3
相关论文
共 31 条
  • [21] Protective immunity induced with malaria vaccine, RTS,S, is linked to Plasmodium falciparum circumsporozoite protein-specific CD4+ and CD8+ T cells producing IFN-γ
    Sun, PF
    Schwenk, R
    White, K
    Stoute, JA
    Cohen, J
    Ballou, WR
    Voss, G
    Kester, KE
    Heppner, DG
    Krzych, U
    JOURNAL OF IMMUNOLOGY, 2003, 171 (12): : 6961 - 6967
  • [22] Neoantigen vaccine-induced CD4 T cells confer protective immunity in a mouse model of multiple myeloma through activation of CD8 T cells against non-vaccine, tumor-associated antigens
    Bekri, Selma
    Rodney-Sandy, Reunet
    Gruenstein, Diana
    Mei, Anna
    Bogen, Bjarne
    Castle, John
    Levey, Daniel
    Cho, Hearn Jay
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 (02)
  • [23] A live experimental vaccine against Burkholderia pseudomallei elicits CD4+ T cell-mediated immunity, priming T cells specific for 2 type III secretion system proteins
    Haque, Ashraful
    Chu, Karen
    Easton, Anna
    Stevens, Mark P.
    Galyov, Edouard E.
    Atkins, Tim
    Titball, Rick
    Bancroft, Gregory J.
    JOURNAL OF INFECTIOUS DISEASES, 2006, 194 (09): : 1241 - 1248
  • [24] H2-M3-restricted CD8+ T cells are not required for MHC class Ib-restricted immunity against Listeria monocytogenes
    D'Orazio, SEF
    Shaw, CA
    Starnbach, MN
    JOURNAL OF EXPERIMENTAL MEDICINE, 2006, 203 (02): : 383 - 391
  • [25] Protection against Mycobacterium tuberculosis Infection Offered by a New Multistage Subunit Vaccine Correlates with Increased Number of IFN-γ+IL-2+ CD4+ and IFN-γ+ CD8+ T Cells
    Wang, Xiaochun
    Zhang, Jingyan
    Liang, Jinping
    Zhang, Ying
    Teng, Xindong
    Yuan, Xuefeng
    Fan, Xionglin
    PLOS ONE, 2015, 10 (03):
  • [26] Immunity against interleukin 4-producing 9L rat glioma is mediated by tumor-specific, interferon-γ producing CD8+ T cells.
    Giezeman-Smits, KM
    Okada, H
    Brissette-Storkus, CS
    Villa, LA
    Attanucci, J
    Tahara, J
    Lotze, MT
    Chambers, WH
    Bozik, ME
    FASEB JOURNAL, 1998, 12 (04): : A278 - A278
  • [27] TARGETING H3.3 K27M MUTATION AS A SHARED NEOANTIGEN IN HLA-A*0201+PATIENTS WITH DIFFUSE MIDLINE GLIOMAS - DEVELOPMENT OF A NOVEL MASS CYTOMETRY-BASED MONITORING OF VACCINE-REACTIVE, EPITOPE-SPECIFIC CD8+T CELL RESPONSES
    Taitt, Jared
    Watchmaker, Payal
    Almeida, Neil
    Okada, Kaori
    Shahin, Maryam
    Mueller, Sabine
    Okada, Hideho
    NEURO-ONCOLOGY, 2019, 21 : 96 - 96
  • [28] Tc17 Cells Mediate Vaccine Immunity against Lethal Fungal Pneumonia in Immune Deficient Hosts Lacking CD4+ T Cells (vol 8, e1002771, 2012)
    Nanjappa, Som Gowda
    PLOS PATHOGENS, 2014, 10 (04)
  • [29] UTILIZING A NOVEL MASS CYTOMETRY-BASED IMMUNOMONITORING PLATFORM FOR THE CHARACTERIZATION OF VACCINE-REACTIVE, EPITOPE-SPECIFIC CD8+ T-CELLS IN HLA-A*0201+ PATIENTS WITH K27M+ DIFFUSE MIDLINE GLIOMAS
    Taitt, Jared
    Watchmaker, Payal
    Nejo, Takahide
    Almeida, Neil
    Okada, Kaori
    Shahin, Maryam
    Gilbert, Ryan
    Mueller, Sabine
    Okada, Hideho
    NEURO-ONCOLOGY, 2019, 21 : 125 - 125
  • [30] Priming and stimulation of hepatitis C virus-specific CD4+ and CD8+ T cells against HCV antigens NS4, NS5a or NS5b from HCV-naive individuals:: implications for prophylactic vaccine
    Li, Wen
    Krishnadas, Deepa K.
    Kumar, Rakesh
    Tyrrell, D. Lorne J.
    Agrawal, Babita
    INTERNATIONAL IMMUNOLOGY, 2008, 20 (01) : 89 - 104
1234