APPLICATION OF MULTICOMPONENT REACTIONS FOR CONSTRUCTION OF QUINOLINE DERIVATIVES

被引：0
作者：
Jha, Anand Mohan [1 ]
机构：
[1] Darbhanga Constituent Unit L N Mithila Univ, M L S M Coll, P G Dept Chem, Darbhanga, Bihar, India
来源：
HETEROCYCLIC LETTERS | 2023年 / 13卷 / 03期
关键词：
Pyranoquinoline; furanoquinoline; Camphor sulfonic acid; Cycloaddition; Organocatalyst; DIELS-ALDER REACTIONS; FACILE SYNTHESIS; CONVENIENT SYNTHESIS; EFFICIENT SYNTHESIS; EPOXIDE OPENINGS; DOMINO REACTION; ACTIVATION; PYRANOQUINOLINE; IMINES; AGENTS;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Camphor sulfonic acid (CSA) catalyzed diastereo selective synthesis of pyrano and furanoquinoline using ABB' type multi-component coupling of aryl amines with cyclic enol ether has been developed. Then in situ generated arylimine reacts with another molecule of electron rich olefines via 4+2 cycloaddition to give pyrano and furanoquinolines in good to excellent yield with high cis diastereoselectivity. Addition of water results in switching the diastereoselectivity towards trans.
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页码：505 / 514
页数：10
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