Rubella Vaccine Uptake among Women of Childbearing Age in Healthcare Settings

被引:1
作者
Ferrari, Cristiana [1 ]
Somma, Giuseppina [1 ]
Gentili, Sandro [1 ]
Manili, Gianmarco [1 ]
Mauro, Gaetano [1 ]
Treglia, Michele [1 ]
Aurilio, Marco Trabucco [2 ]
Magrini, Andrea [1 ]
Coppeta, Luca [1 ]
机构
[1] Univ Roma Tor Vergata, Dept Biomed & Prevent, I-00133 Rome, Italy
[2] Italian Natl Social Secur Inst INPS, Off Med Forens Coordinat, I-00144 Rome, Italy
关键词
rubella vaccine; rubella; vaccination strategy; immunity for rubella; hesitancy; vaccine acceptance; INFLUENZA VACCINATION; WORKERS; MEASLES; HESITANCY; COVID-19; MUMPS; INTENTION;
D O I
10.3390/healthcare11222992
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Background: Rubella is a contagious viral infection that occurs most often in children and young adults. Rubella is the leading vaccine-preventable cause of birth defects. Rubella infection in pregnant women may cause fetal death or congenital defects known as congenital rubella syndrome. There is no specific treatment for rubella, but the disease is preventable by vaccination with an efficacy of over 95%. Vaccination coverage is still below the recommended levels and many cases have occurred worldwide. The COVID-19 pandemic has had a negative impact on the immunization programs and the quality of disease surveillance worldwide. Operators of the healthcare setting are at increased risk of infection due to their work duties and should receive preventive vaccination or serologic protection to work in a healthcare setting. Aims: To evaluate the serological evidence of rubella IgG antibodies in female healthcare operators of childbearing age, to assess the risk of a breakthrough infection and the need for an additional dose of vaccine. Methods: We collected age and antibody titers from 449 young female operators aged <50 years who underwent the periodic surveillance at the Occupational Medicine Unit of the Policlinico Tor Vergata, Rome, from January to July 2022. Subjects were considered immune if the anti-rubella IgG titer was >11.00 IU/mL. Results: The rate of serologically unprotected subjects was 9.13% (41/449). The mean age of protected subjects was 26.93 years, while the mean age of unprotected subjects was 28.24 years. Age did not correlate with mean titer on statistical analysis (p = 0.10). The acceptance rate among unprotected operators was 31.7%. A positive attitude towards vaccination was found in 11/28 (39.3%) of the unvaccinated subjects, while a negative tendency was found in 2/28 (7.1%) of these subjects; most of the unvaccinated operators 15/28 (53.6%) prefer to postpone the administration of the vaccine. When compared with a similar population from the pre-pandemic period, the actual proportion of immune female subjects was not significantly different from that found in 2019 (90.87% vs. 90.3%). Conclusions: Protection against rubella was suboptimal among female healthcare workers of childbearing age. Acceptance of the rubella vaccine among these operators was low. Most of those who were hesitant intended to postpone the vaccination, while a minority had negative attitudes toward vaccination. A policy of mandatory vaccination policy should overcome the reluctance of operators.
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相关论文
共 49 条
[1]   Main Predictors of COVID-19 Vaccination Uptake among Italian Healthcare Workers in Relation to Variable Degrees of Hesitancy: Result from a Cross-Sectional Online Survey [J].
Aurilio, Marco Trabucco ;
Mennini, Francesco Saverio ;
Ferrari, Cristiana ;
Somma, Giuseppina ;
Di Giampaolo, Luca ;
Bolcato, Matteo ;
De-Giorgio, Fabio ;
Muscatello, Roberto ;
Magrini, Andrea ;
Coppeta, Luca .
TROPICAL MEDICINE AND INFECTIOUS DISEASE, 2022, 7 (12)
[2]   Successes and challenges for preventing measles, mumps and rubella by vaccination [J].
Bankamp, Bettina ;
Hickman, Carole ;
Icenogle, Joseph P. ;
Rota, Paul A. .
CURRENT OPINION IN VIROLOGY, 2019, 34 :110-116
[3]   Pervasive Parental Hesitancy and Resistance towards Measles Rubella Vaccination in Jordan [J].
Barakat, Muna ;
Abdaljaleel, Maram ;
Atawneh, Nada ;
Alkhazaleh, Rawan ;
Aburumman, Dana ;
Hamed, Eman ;
Sallam, Malik .
VACCINES, 2023, 11 (11)
[4]   Prevalence and management of rubella susceptibility in healthcare workers in Italy: A systematic review and meta-analysis [J].
Bianchi, Francesco Paolo ;
Stefanizzi, Pasquale ;
Diella, Giusy ;
Martinelli, Andrea ;
Di Lorenzo, Antonio ;
Gallone, Maria Serena ;
Tafuri, Silvio .
VACCINE: X, 2022, 12
[5]   Measles immunity in healthcare workers of an Italian hospital [J].
Camilloni, Barbara ;
Stracci, Fabrizio ;
De Lio, Maria Cristina ;
Mencacci, Antonella ;
Cenci, Elio ;
Bozza, Silvia .
JOURNAL OF INFECTION AND PUBLIC HEALTH, 2020, 13 (08) :1123-1125
[6]  
cdc, Immunization of Health-Care Workers: Recommendations of the Advisory Committee on Immunization Practices (ACIP) and the Hospital Infection Control Practices Advisory Committee (HICPAC)
[7]  
Centers for Disease Control and Prevention (CDC), 2005, MMWR Morb. Mortal. Wkly. Rep, V54, P175
[8]   Persistence of antibodies for measles among vaccinated medical students in Italy [J].
Coppeta, Luca ;
Somma, Giuseppina ;
Di Giampaolo, Luca ;
Bizzarro, Giuseppe ;
Ippoliti, Lorenzo ;
Borelli, Francesco ;
Balbi, Ottavia ;
Perrone, Stefano ;
Pietroiusti, Antonio .
INFECTIOUS DISEASES, 2020, 52 (08) :593-595
[9]   Susceptibility to measles among healthcare workers: a cross-sectional serological study [J].
Coppeta, Luca ;
Biondi, Giorgia ;
Perrone, Stefano ;
Pietroiusti, Antonio .
INFECTIOUS DISEASES, 2020, 52 (06) :443-445
[10]   Pre-vaccination IgG screening for mumps is the most cost-effectiveness immunization strategy among Health Care Workers [J].
Coppeta, Luca ;
Balbi, Ottavia ;
Baldi, Savino ;
Pietroiusti, Antonio ;
Magrini, Andrea .
HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2019, 15 (05) :1135-1138