A practical guide to prescribing sublingual immunotherapy tablets in North America for pediatric allergic rhinoconjunctivitis: an injection-free allergy immunotherapy option

被引:3
作者
Blaiss, Michael [1 ]
DuBuske, Lawrence [2 ]
Nolte, Hendrik [3 ]
Opstrup, Morten [4 ]
Rance, Karen [3 ]
机构
[1] Med Coll Georgia, Dept Pediat, Augusta, GA USA
[2] George Washington Univ Hosp, Dept Med, Washington, DC USA
[3] ALK, Bedminster, NJ 07921 USA
[4] ALK Abello A S, Horsholm, Denmark
关键词
allergic rhinitis; allergen immunotherapy; children; checklist; decision tree; management; sublingual; ADVERSE EVENT PROFILE; TIMOTHY GRASS; SLIT-TABLET; RHINITIS; EFFICACY; SAFETY; CHILDREN; MANAGEMENT; COMORBIDITIES; ADOLESCENTS;
D O I
10.3389/fped.2023.1244146
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Allergic rhinoconjunctivitis (ARC) is a common disease that affects individuals of all ages. Pediatricians may be the first (and only) point of care for children with ARC. Sublingual immunotherapy (SLIT)-tablets are a convenient at-home, injection-free allergy immunotherapy option that can be used for the treatment of ARC. This paper provides a practical guide for pediatricians to aid in prescribing SLIT-tablets to children with ARC in North America. Topics include a summary of the available SLIT-tablets and their efficacy and safety, guidance on when SLIT-tablets are an appropriate option, and how to diagnose ARC and identify culprit allergens. Practical guidance is also provided through a proposed decision tree, a prescribing checklist and prescribing procedures, and suggested follow-up assessments.
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收藏
页数:9
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共 62 条
[1]   Allergy management in primary care across European countries - actual status [J].
Agache, I. ;
Ryan, D. ;
Rodriguez, M. R. ;
Yusuf, O. ;
Angier, E. ;
Jutel, M. .
ALLERGY, 2013, 68 (07) :836-843
[2]   You sneeze, you lose: The impact of pollen exposure on cognitive performance during high-stakes high school exams [J].
Bensnes, Simon Sobstad .
JOURNAL OF HEALTH ECONOMICS, 2016, 49 :1-13
[3]  
Bernstein D, 2023, J ALLERGY CLIN IMMUN, V151, pAB125
[4]   A practical guide to the sublingual immunotherapy tablet adverse event profile: implications for clinical practice [J].
Bernstein, David I. ;
Bardelas, Jose A., Jr. ;
Fogh, Bodil Svanholm ;
Kaur, Amarjot ;
Li, Ziliang ;
Nolte, Hendrik .
POSTGRADUATE MEDICINE, 2017, 129 (06) :590-597
[5]   The SQ tree SLIT-tablet is highly effective and well tolerated: Results from a randomized, double-blind, placebo-controlled phase III trial [J].
Biedermann, Tilo ;
Kuna, Piotr ;
Panzner, Petr ;
Valovirta, Erkka ;
Andersson, Morgan ;
de Blay, Frederic ;
Thrane, Dorthe ;
Jacobsen, Sanja Hald ;
Stage, Brian Sonne ;
Winther, Lone .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2019, 143 (03) :1058-+
[6]   Efficacy and safety of timothy grass allergy immunotherapy tablets in North American children and adolescents [J].
Blaiss, Michael ;
Maloney, Jennifer ;
Nolte, Hendrik ;
Gawchik, Sandra ;
Yao, Ruji ;
Skoner, David P. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2011, 127 (01) :64-U127
[7]   Diagnosis and treatment of nasal and ocular allergies: the Allergies, Immunotherapy, and RhinoconjunctivitiS (AIRS) surveys [J].
Blaiss, Michael S. ;
Dykewicz, Mark S. ;
Skoner, David P. ;
Smith, Nancy ;
Leatherman, Bryan ;
Craig, Timothy J. ;
Bielory, Leonard ;
Walstein, Nicole ;
Allen-Ramey, Felicia .
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2014, 112 (04) :322-+
[8]   Administration and Burden of Subcutaneous Immunotherapy for Allergic Rhinitis in US and Canadian Clinical Practice [J].
Blume, Steven W. ;
Yeomans, Karen ;
Allen-Ramey, Felicia ;
Smith, Nancy ;
Kim, Harold ;
Lockey, Richard F. ;
Nichol, Michael B. .
JOURNAL OF MANAGED CARE & SPECIALTY PHARMACY, 2015, 21 (11) :982-990
[9]   Sublingual immunotherapy tablets as a disease-modifying add-on treatment option to pharmacotherapy for allergic rhinitis and asthma [J].
Brunton, Stephen ;
Nelson, Harold S. ;
Bernstein, David I. ;
Lawton, Simon ;
Lu, Susan ;
Nolte, Hendrik .
POSTGRADUATE MEDICINE, 2017, 129 (06) :581-589
[10]   Safety and efficacy in children of an SQ-standardized grass allergen tablet for sublingual immunotherapy [J].
Bufe, Albrecht ;
Eberle, Peter ;
Franke-Beckmann, Eivy ;
Funck, Juergen ;
Kimmig, Martin ;
Klimek, Ludger ;
Knecht, Roland ;
Stephan, Volker ;
Tholstrup, Bente ;
Weisshaar, Christian ;
Kaiser, Friedrich .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2009, 123 (01) :167-173