Epidemiology and outcomes of choledocholithiasis and cholangitis in the United States: trends and urban-rural variations

被引:12
作者
Li, Suqing [1 ]
Guizzetti, Leonardo [2 ]
Ma, Christopher [1 ,2 ,3 ]
Shaheen, Abdel Aziz [1 ,3 ]
Dixon, Elijah [4 ]
Ball, Chad [4 ]
Wani, Sachin [5 ]
Forbes, Nauzer [1 ,3 ]
机构
[1] Univ Calgary, Dept Med, Div Gastroenterol & Hepatol, TRW 6D62,3280 Hosp Drive NW, Calgary, AB T2N 4Z6, Canada
[2] Alimentiv Inc, London, ON, Canada
[3] Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada
[4] Univ Calgary, Dept Surg, Calgary, AB, Canada
[5] Univ Colorado Anschutz Med Campus, Div Gastroenterol & Hepatol, Aurora, CO USA
关键词
Choledocholithiasis; Cholangitis; Endoscopic retrograde cholangiopancreatography; Mortality; Epidemiology; BILE-DUCT STONES; GALLBLADDER-DISEASE; RISK-FACTORS; MANAGEMENT; CHOLANGIOGRAPHY; CHOLECYSTECTOMY; EXPLORATION; NATIONWIDE; ERCP;
D O I
10.1186/s12876-023-02868-3
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
BackgroundGallstone disease poses a significant health burden in the United States. Choledocholithiasis and cholangitis are common complications of gallstone disease for which data on current epidemiological trends are lacking. We aimed to evaluate temporal changes in hospitalization, management, and outcomes for patients with choledocholithiasis and cholangitis.MethodsThe National Inpatient Sample was used to identify discharges for choledocholithiasis and cholangitis between 2005 and 2014. Temporal trends were evaluated via annual percent changes (APCs). Joinpoint regression was used to assess inflection points. Multivariable regression models were used to evaluate associations of interest.ResultsFrom 189,362 unweighted discharges for choledocholithiasis and/or cholangitis, there was an increase in discharges for choledocholithiasis (APC 2.3%, 95% confidence intervals, CI, 1.9-2.7%) and cholangitis (APC 1.5%, 95% CI 0.7-2.2%). Procedural interventions were more likely at urban hospitals for choledocholithiasis (adjusted odds ratio, aOR, 2.94, 95% CI 2.72 to 3.17) and cholangitis (aOR 2.97, 95% CI 2.50 to 3.54). In-hospital mortality significantly decreased annually for choledocholithiasis (aOR 0.90, 95% CI 0.88 to 0.93) and cholangitis (aOR 0.93, 95% CI 0.89 to 0.97). In-hospital mortality between rural and urban centers was comparable for choledocholithiasis (aOR 1.16, 95% CI 0.89 to 1.52) and cholangitis (aOR 1.12, 95% CI 0.72 to 1.72).ConclusionsHospitalizations for choledocholithiasis and cholangitis have increased between 2005 and 2014, reflecting a growing burden of gallstone disease. Hospital mortality between urban and rural centers is similar, however urban centers have a higher rate of procedural interventions suggesting limitations to accessing procedural interventions at rural centers.
引用
收藏
页数:12
相关论文
共 46 条
  • [1] Abbas A., 2018, OFFICIAL J AM COLL G, V113, P35
  • [2] Abbas A., 2018, OFFICIAL J AM COLL G, V113, P34, DOI [10.14309/00000434-201810001-00056, DOI 10.14309/00000434-201810001-00056]
  • [3] Trends in Post-Therapeutic Endoscopic Retrograde Cholangiopancreatography Gastrointestinal Hemorrhage, Perforation and Mortality from 2000 to 2012: A Nationwide Study
    Afridi, Faiz
    Rotundo, Laura
    Feurdean, Mirela
    Ahlawat, Sushil
    [J]. DIGESTION, 2019, 100 (02) : 100 - 108
  • [4] Ahmed A, 2000, AM FAM PHYSICIAN, V61, P1673
  • [5] Ahmed Monjur, 2018, World J Gastrointest Pathophysiol, V9, P1, DOI 10.4291/wjgp.v9.i1.1
  • [6] Retrospective comparative analysis of choledochoscopic bile duct exploration versus ERCP for bile duct stones
    Al-Habbal, Y.
    Reid, I.
    Tiang, T.
    Houli, N.
    Lai, B.
    McQuillan, T.
    Bird, D.
    Yong, T.
    [J]. SCIENTIFIC REPORTS, 2020, 10 (01)
  • [7] Increasing bile duct injury and decreasing utilization of intraoperative cholangiogram and common bile duct exploration over 14 years: an analysis of outcomes in New York State
    Altieri, Maria S.
    Yang, Jie
    Obeid, Nabeel
    Zhu, Chencan
    Talamini, Mark
    Pryor, Aurora
    [J]. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2018, 32 (02): : 667 - 674
  • [8] Surgeons, ERCP, and laparoscopic common bile duct exploration: do we need a standard approach for common bile duct stones?
    Baucom, Rebeccah B.
    Feurer, Irene D.
    Shelton, Julia S.
    Kummerow, Kristy
    Holzman, Michael D.
    Poulose, Benjamin K.
    [J]. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2016, 30 (02): : 414 - 423
  • [9] Laparoscopic cholecystectomy: first, do no harm; second, take care of bile duct stones
    Berci, George
    Hunter, John
    Morgenstern, Leon
    Arregui, Maurice
    Brunt, Michael
    Carroll, Brandon
    Edye, Michael
    Fermelia, David
    Ferzli, George
    Greene, Frederick
    Petelin, Joseph
    Phillips, Edward
    Ponsky, Jeffrey
    Sax, Harry
    Schwaitzberg, Steven
    Soper, Nathaniel
    Swanstrom, Lee
    Traverso, William
    [J]. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2013, 27 (04): : 1051 - 1054
  • [10] EAES rapid guideline: updated systematic review, network meta-analysis, CINeMA and GRADE assessment, and evidence-informed European recommendations on the management of common bile duct stones
    Boni, Luigi
    Huo, Bright
    Alberici, Laura
    Ricci, Claudio
    Tsokani, Sofia
    Mavridis, Dimitris
    Amer, Yasser Sami
    Andreou, Alexandros
    Berriman, Thomas
    Donatelli, Gianfranco
    Forbes, Nauzer
    Kapiris, Stylianos
    Kayaalp, Cuneyt
    Kylanpaa, Leena
    Parra-Membrives, Pablo
    Siersema, Peter D.
    Black, George F.
    Antoniou, Stavros A.
    [J]. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2022, 36 (11): : 7863 - 7876