Mechanisms of Cardiac Repair in Cell Therapy

被引：2
|
作者：
Collet, Berenice C. [1 ,2 ]
Davis, Darryl R. [1 ,2 ,3 ]
机构：
[1] Univ Ottawa, Heart Inst, Dept Med, Div Cardiol, Ottawa, ON, Canada
[2] Univ Ottawa, Dept Cellular & Mol Med, Ottawa, ON, Canada
[3] Univ Ottawa, Heart Inst, H3214,40 Ruskin St, Ottawa, ON K1Y 4W7, Canada
来源：
HEART LUNG AND CIRCULATION | 2023年 / 32卷 / 07期
基金：
加拿大自然科学与工程研究理事会; 加拿大健康研究院;
关键词：
Heart failure; Cell therapy; Regeneration; Myocardial infarction; ACUTE MYOCARDIAL-INFARCTION; ENDOTHELIAL PROGENITOR CELLS; CARDIOSPHERE-DERIVED CELLS; LEFT-VENTRICULAR FUNCTION; MARROW MONONUCLEAR-CELLS; HEMATOPOIETIC STEM-CELLS; CHRONIC HEART-FAILURE; INTRACORONARY INJECTION; ISCHEMIC CARDIOMYOPATHY; TRANSPLANTATION;
D O I：
10.1016/j.hlc.2023.01.019
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Heart failure is an important cause of morbidity and mortality. More than 20 years ago, special interest was drawn to cell therapy as a means of restoring damaged hearts to working condition. But progress has not been straightforward as many of our initial assumptions turned out to be wrong. In this review, we critically examine the last 20 years of progress in cardiac cell therapy and focus on several of the popular beliefs surrounding cell therapy to illustrate the mechanisms involved in restoring heart function after cardiac injury. Are they true or false?
引用
收藏
页码：825 / 835
页数：11
相关论文
共 50 条
  • [1] Autologous cell therapy for cardiac repair
    Davis, Darryl R.
    Stewart, Duncan J.
    EXPERT OPINION ON BIOLOGICAL THERAPY, 2011, 11 (04) : 489 - 508
  • [2] At a Crossroad Cell Therapy for Cardiac Repair
    Deutsch, Marcus-Andre
    Sturzu, Anthony
    Wu, Sean M.
    CIRCULATION RESEARCH, 2013, 112 (06) : 884 - 890
  • [3] Cardiac Cell Therapy: Insights into the Mechanisms of Tissue Repair
    Peng, Hsuan
    Shindo, Kazuhiro
    Donahue, Renee R.
    Abdel-Latif, Ahmed
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (03) : 1 - 15
  • [4] Cell therapy for cardiac repair
    Lee, Joon
    Terracciano, Cesare M.
    BRITISH MEDICAL BULLETIN, 2010, 94 (01) : 65 - 80
  • [5] Cardiac stem cell therapy: Have we put too much hype in which cell type to use?
    Ye, Jianqin
    Yeghiazarians, Yerem
    HEART FAILURE REVIEWS, 2015, 20 (05) : 613 - 619
  • [6] Stem Cell Therapy for Cardiac Repair
    Collins, John M.
    Russell, Brenda
    JOURNAL OF CARDIOVASCULAR NURSING, 2009, 24 (02) : 93 - 97
  • [7] Cell tracking in cardiac repair: what to image and how to image
    Ruggiero, Alessandro
    Thorek, Daniel L. J.
    Guenoun, Jamal
    Krestin, Gabriel P.
    Bernsen, Monique R.
    EUROPEAN RADIOLOGY, 2012, 22 (01) : 189 - 204
  • [8] Cardiac Cell Repair Therapy: A Clinical Perspective
    Gersh, Bernard J.
    Simari, Robert D.
    Behfar, Atta
    Terzic, Carmen M.
    Terzic, Andre
    MAYO CLINIC PROCEEDINGS, 2009, 84 (10) : 876 - 892
  • [9] From state-of-the-art cell therapy to endogenous cardiac repair
    Mohl, Werner
    Henry, Timothy D.
    Milasinovic, Dejan
    Nguemo, Filomain
    Hescheler, Juergen
    Perin, Emerson C.
    EUROINTERVENTION, 2017, 13 (06) : 760 - 772
  • [10] Cell therapy for cardiac repair-lessons from clinical trials
    Behfar, Atta
    Crespo-Diaz, Ruben
    Terzic, Andre
    Gersh, Bernard J.
    NATURE REVIEWS CARDIOLOGY, 2014, 11 (04) : 232 - 246
12345