Imaging biomarker for quantitative analysis of endometrial injury based on optical coherence tomography/ultrasound integrated imaging mode

被引：1

作者：

Du, Meng ^{[1
,2
]}

Zhang, Jinke

Wang, Ting ^{[1
,2
]}

Fang, Jinghui ^{[4
]}

Su, Hanyinghong ^{[2
]}

Xiao, Zhang ^{[5
]}

Peng, Yingao ^{[2
]}

Liang, Xiaowen ^{[2
]}

Gong, Xiaojing ^{[3
,8
]}

Chen, Zhiyi ^{[1
,2
,6
,7
]}

机构：

[1] Univ South China, Affiliated Hosp 1, Med Imaging Ctr, Hengyang Med Sch, Hengyang, Hunan, Peoples R China

[2] Univ South China, Inst Med Imaging, Hengyang Med Sch, Hengyang, Peoples R China

[3] Chinese Acad Sci, Res Ctr Biomed Opt & Mol Imaging, Shenzhen Key Lab Mol Imaging, Guangdong Prov Key Lab Biomed Opt Imaging Technol,, Shenzhen 518055, Peoples R China

[4] Guangzhou Med Univ, Affiliated Hosp 3, Dept Ultrasound Med, Lab Ultrasound Mol Imaging, Guangzhou, Guangdong, Peoples R China

[5] Univ South China, Coll Mech Engn, Hengyang, Peoples R China

[6] Univ South China, Affiliated Hosp 7, Hunan Vet Adm Hosp, Hengyang Med Sch, Changsha, Hunan, Peoples R China

[7] Univ South China, Affiliated Hosp 1, Med Imaging Ctr, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China

[8] Chinese Acad Sci, Shenzhen Inst Adv Technol, Res Ctr Biomed Opt & Mol Imaging,CAS Key Lab Hlth, Shenzhen Key Lab Mol Imaging,Guangdong Prov Key La, Shenzhen 518055, Guangdong, Peoples R China

来源：

JOURNAL OF BIOPHOTONICS | 2023年 / 16卷 / 12期

关键词：

endometrial injury; endoscopic imaging; imaging biomarker; optical coherence tomography; quantitative analysis; ultrasound; TOMOGRAPHY; OCT;

D O I：

10.1002/jbio.202300113

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Precise evaluation of endometrial injury is significant to clinical decision-making in gynecological disease and assisted reproductive technology. However, there is a lack of assessment methods for endometrium in vivo. In this research, we intend to develop quantitative imaging markers with optical coherence tomography (OCT)/ultrasound (US) integrated imaging system through intrauterine endoscopic imaging. OCT/US integrated imaging system was established as our previous research reported. The endometrial injury model was established and after treatment, OCT/US integrated imaging and uterus biopsy was performed to evaluate the endometrial thickness, number of superficial fold, and intrauterine area. According to the results, three quantitative indexes acquired from OCT/US image and HE staining have the same trend and have a strong relationship with the severity of the endometrial injury. Accordingly, we developed three imaging markers for quantitative analysis of endometrial injury in vivo, which provided a precise mode for endometrium evaluation in clinical practice.

引用

页数：9

共 32 条

[31] Construction and Optimization of an Endometrial Injury Model in Mice by Transcervical Ethanol Perfusion
Zhang, Shenghui
Sun, Yuliang
Jiang, Dongli
Chen, Tongtong
Liu, Ruihong
Li, Xinyi
Lu, Yilin
Qiao, Liang
Pan, Ying
Liu, Yanli
Lin, Juntang
[J]. REPRODUCTIVE SCIENCES, 2021, 28 (03) : 693 - 702
[32] Optical Coherence Tomography for Three-Dimensional Imaging in the Biomedical Field: A Review
Zheng, Shu
Bai, Yanru
Xu, Zihao
Liu, Pengfei
Ni, Guangjian
[J]. FRONTIERS IN PHYSICS, 2021, 9

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