Efficacy and safety of cardiac resynchronization therapy in chemotherapy-induced cardiomyopathy: A systematic review

被引:0
|
作者
Shehram, Muhammad [1 ]
Khalid, Hiba [2 ]
Shafique, Hafiz Muhammad [3 ]
Umer, Bakht [3 ]
Zafar, Awais [4 ]
Ullah, Asif [5 ]
Zaidi, Syed Muhammad Jawad [6 ]
Basit, Jawad [6 ]
Mehmoodi, Amin [7 ]
Malik, Jahanzeb [6 ]
机构
[1] Mufti Mehmood Mem Teaching Hosp, Dept Cardiol, Dera Ismail Khan, Pakistan
[2] Benazir Bhutto Hosp, Dept Dermatol, Rawalpindi, Pakistan
[3] Armed Forces Inst Cardiol, Dept Intervent Cardiol, Rawalpindi, Pakistan
[4] Sahiwal Med Coll, Dept Med, Sahiwal, Pakistan
[5] Khyber Med Univ, Inst Med Sci, Dept Cardiol, Kohat, Pakistan
[6] Cardiovasc Analyt Grp, Dept Cardiovasc Med, Canterbury, England
[7] Ibn e Seen Hosp, Dept Med, Kabul, Afghanistan
关键词
anthracycline; diastolic dysfunction; ejection fraction; heart failure; HEART-FAILURE; CARDIOTOXICITY; PREVENTION;
D O I
10.1111/anec.13070
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
ObjectiveThe aim of the study was to assess the efficacy of cardiac resynchronization therapy (CRT) in patients with chemotherapy-induced cardiomyopathy (CIC). MethodsWith the increasing incidence of CIC, the association of CRT with improvement in clinical outcomes, echocardiographic parameters, and New York Heart Classification (NYHA) class was assessed through this qualitative systematic review. ResultsThe five studies included a total of 169 patients who underwent CRT after CIC, and of these, 61 (36.1%) patients were males. All studies showed an improvement in left ventricular ejection fraction (LVEF), among other echocardiographic parameters of LV volume. However, these findings are limited by short follow-up periods, small sample sizes, and the absence of a control group. ConclusionCRT was associated with improvement in all patient parameters with CIC.
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页数:6
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