Dexmedetomidine A Sedation Alternative in the Intensive Care Setting

被引:4
作者
Thomas, Amy [1 ]
Ullrich, Marie [1 ,2 ]
机构
[1] Point Loma Nazarene Univ, San Diego, CA USA
[2] 2580 Northside Dr,Apt 304, San Diego, CA 92108 USA
关键词
dexmedetomidine (PRECEDEX); effects; intensive care unit; sedation; uses; BENZODIAZEPINES; METAANALYSIS; PROPOFOL; DELIRIUM; UNIT;
D O I
10.1097/CNQ.0000000000000458
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
In the last 20 years, the occurrences of drug shortages have increased in frequency as well as duration before returning to the mainstream market. This has prompted intensive care unit nurses and medical staff to seek alternate medication infusion options that provide safe yet effective sedation for patients admitted to intensive care units across the country. Dexmedetomidine (PRECEDEX) emerged in 1999 after the Federal Drug Administration approved it for intensive care use but was quickly embraced by anesthesia providers as it rendered patients undergoing procedures or surgery with adequate analgesia and sedation. Dexmedetomidine (PRECEDEX) continued to maintain patients who required short-term intubation and mechanical ventilation with adequate sedation throughout the entire perioperative period. With patients remaining hemodynamically stable in the initial postoperative period, critical care nurses embraced the use of dexmedetomidine (PRECEDEX) in the intensive care unit setting. As dexmedetomidine (PRECEDEX) gained popularity, it has been used to help manage multiple disease processes such as delirium, agitation, alcoholic withdrawal, and anxiety. Dexmedetomidine (PRECEDEX) has been indicated to be a safer alternative to benzodiazepines, narcotics, or propofol (Diprivan), while providing adequate sedation and allowing patients to maintain hemodynamic stability.
引用
收藏
页码:271 / 276
页数:6
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[41]   Comparison between dexmedetomidine and propofol for sedation in the intensive care unit: patient and clinician perceptions [J].
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