In silico study of magnetic nanoparticles transport in channels of various diameters in the presence of a constant magnetic field

被引：4
|
作者：
Starodumov, Ilya O. O. [1 ,2 ]
Sokolov, Sergey Yu. [1 ,2 ]
Blyakhman, Felix S. A. [1 ,2 ]
Zubarev, Andrey Yu. [3 ]
Fedotov, Sergei P. P. [4 ]
Alexandrov, Dmitri V. V. [1 ,3 ]
机构：
[1] Ural Fed Univ, Dept Fundamental & Appl Phys, Lab Multiphase Phys & Biol Media Modeling, Ekaterinburg 620000, Russia
[2] Ural State Med Univ, Dept Biomed Phys & Engn, Ekaterinburg 620028, Russia
[3] Ural Fed Univ, Dept Theoret & Math Phys, Lab Multiscale Math Modeling, Lab Stochast Transport Nanoparticles Living Syst, Ekaterinburg 620000, Russia
[4] Univ Manchester, Dept Math, Manchester M13 9PL, England
来源：
EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS | 2023年 / 232卷 / 08期
基金：
俄罗斯科学基金会;
关键词：
HYPERTHERMIA; HYDROGELS;
D O I：
10.1140/epjs/s11734-023-00859-9
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
In general, this study is concerned with the development of theoretical basis for the use of magnetic nanoparticles (MNPs) for the needs of cardiology. A mathematical model reflecting the fundamental features of MNPs motion and transport in a liquid that flows in a channel modeling a stenotic blood vessel is introduced. The obtained results of computational simulations of MNPs transport revealed the presence of stagnant zones with vortices of the host liquid that appear near the stenosis. The application of a magnetic field to the channel provokes the accumulation of MNPs in these zones. An increased MNPs concentration near the stenosis makes it possible to determine the position and size of the stenosis using an external magnetic sensor.
引用
收藏
页码：1207 / 1217
页数：11
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