Effect of Standing Intravenous Acetaminophen on Postoperative Opioid Exposure in a Pediatric Cardiac Intensive Care Unit

被引：5
作者：
Torres, Chelsea M. [1 ,2 ]
Geneslaw, Andrew S. [3 ]
Svoboda, Leanne [4 ]
Smerling, Arthur J. [3 ]
Metitiri, Katherine R. Schlosser [3 ]
机构：
[1] Columbia Univ, Dept Pediat, Irving Med Ctr, New York Presbyterian Morgan Stanley Childrens Ho, New York, NY 10027 USA
[2] Univ S Florida, Dept Pediat, Div Gen Acad Pediat, 2 Tampa Gen Circle,5th Floor, Tampa, FL 33606 USA
[3] Columbia Univ, Irving Med Ctr, Dept Pediat, Div Crit Care & Hosp Med,New York Presbyterian Mo, New York, NY USA
[4] New York Presbyterian Morgan Stanley Childrens Ho, Dept Pharm, New York, NY USA
来源：
JOURNAL OF PEDIATRICS | 2023年 / 255卷
关键词：
NONSTEROIDAL ANTIINFLAMMATORY DRUGS; SURGERY; PARACETAMOL; METAANALYSIS; ANALGESICS; PAIN;
D O I：
10.1016/j.jpeds.2022.12.003
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
This study assessed the association between standing intravenous acetaminophen and opioid exposure after cardiac surgery. Before vs after implementation of a standardized pain pathway, we report decreased opioid exposure, 0.38 milligram per kilogram of morphine equivalents [IQR 0.10-0.81] vs 0.26 milligram per kilogram of morphine equivalents [0.09-0.56] (P =.01) and increased acetaminophen exposure, 3 [2-4] vs 4 [4-5] doses (P <.001).
引用
收藏
页码：236 / +
页数：6
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