Effect of Standing Intravenous Acetaminophen on Postoperative Opioid Exposure in a Pediatric Cardiac Intensive Care Unit

被引：5

作者：

Torres, Chelsea M. ^{[1
,2
]}

Geneslaw, Andrew S. ^{[3
]}

Svoboda, Leanne ^{[4
]}

Smerling, Arthur J. ^{[3
]}

Metitiri, Katherine R. Schlosser ^{[3
]}

机构：

[1] Columbia Univ, Dept Pediat, Irving Med Ctr, New York Presbyterian Morgan Stanley Childrens Ho, New York, NY 10027 USA

[2] Univ S Florida, Dept Pediat, Div Gen Acad Pediat, 2 Tampa Gen Circle,5th Floor, Tampa, FL 33606 USA

[3] Columbia Univ, Irving Med Ctr, Dept Pediat, Div Crit Care & Hosp Med,New York Presbyterian Mo, New York, NY USA

[4] New York Presbyterian Morgan Stanley Childrens Ho, Dept Pharm, New York, NY USA

来源：

JOURNAL OF PEDIATRICS | 2023年 / 255卷

关键词：

NONSTEROIDAL ANTIINFLAMMATORY DRUGS; SURGERY; PARACETAMOL; METAANALYSIS; ANALGESICS; PAIN;

D O I：

10.1016/j.jpeds.2022.12.003

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

This study assessed the association between standing intravenous acetaminophen and opioid exposure after cardiac surgery. Before vs after implementation of a standardized pain pathway, we report decreased opioid exposure, 0.38 milligram per kilogram of morphine equivalents [IQR 0.10-0.81] vs 0.26 milligram per kilogram of morphine equivalents [0.09-0.56] (P =.01) and increased acetaminophen exposure, 3 [2-4] vs 4 [4-5] doses (P <.001).

引用

页码：236 / +

页数：6

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