Recent Development of Nanomaterials for Transdermal Drug Delivery

被引：31

作者：

Leong, Moong Yan ^{[1
]}

Kong, Yeo Lee ^{[2
]}

Burgess, Kevin ^{[3
]}

Wong, Won Fen ^{[4
]}

Sethi, Gautam ^{[5
]}

Looi, Chung Yeng ^{[1
]}

机构：

[1] Taylors Univ Lakeside Campus, Fac Hlth & Med Sci, Sch Biosci, Subang Jaya 47500, Selangor, Malaysia

[2] Taylors Univ Lakeside Campus, Dept Engn & Appl Sci, America Degree Program, Subang Jaya 47500, Selangor, Malaysia

[3] Texas A&M Univ, Dept Chem, POB 30012, College Stn, TX 77842 USA

[4] Univ Malaya, Fac Med, Dept Med Microbiol, Kuala Lumpur 50603, Malaysia

[5] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Singapore 117600, Singapore

来源：

BIOMEDICINES | 2023年 / 11卷 / 04期

基金：

英国科研创新办公室;

关键词：

nanomaterials; transdermal drug delivery; transdermal mechanisms; POLY(LACTIC-CO-GLYCOLIC ACID) NANOPARTICLES; BACTERIAL CELLULOSE MEMBRANES; COPPER SULFIDE NANOPARTICLES; IRON-OXIDE NANOPARTICLES; IN-VITRO EVALUATION; OF-THE-ART; MAGNETIC NANOPARTICLES; PLGA NANOPARTICLES; IONIC LIQUIDS; RUBBER LATEX;

D O I：

10.3390/biomedicines11041124

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nano-engineered medical products first appeared in the last decade. The current research in this area focuses on developing safe drugs with minimal adverse effects associated with the pharmacologically active cargo. Transdermal drug delivery, an alternative to oral administration, offers patient convenience, avoids first-pass hepatic metabolism, provides local targeting, and reduces effective drug toxicities. Nanomaterials provide alternatives to conventional transdermal drug delivery including patches, gels, sprays, and lotions, but it is crucial to understand the transport mechanisms involved. This article reviews the recent research trends in transdermal drug delivery and emphasizes the mechanisms and nano-formulations currently in vogue.

引用

页数：27

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