Two Cases of Familial Mediterranean Fever Involving MEFV Variants: The Importance of Differentiating the Diagnosis from COVID-19

被引：0

作者：

Nakayama, Tomohiro ^{[1
,2
]}

Kozu, Yutaka ^{[3
]}

机构：

[1] Nihon Univ, Sch Med, Dept Pathol & Microbiol, Div Lab Med, Tokyo, Japan

[2] Nihon Univ, Sch Med, Dept Pathol & Microbiol, Technol Dev Dis Prote Div, Tokyo, Japan

[3] Nihon Univ, Sch Med, Dept Internal Med, Div Resp Med, Tokyo, Japan

来源：

INTERNAL MEDICINE | 2023年 / 62卷 / 04期

关键词：

COVID-19; familial Mediterranean fever; MEFV gene; SARS-CoV-2; MUTATIONS; GENE;

D O I：

10.2169/internalmedicine.0414-22

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Familial Mediterranean fever (FMF) is an inherited autoinflammatory disease associated with the MEFV gene. FMF is common in Mediterranean peoples but not highly recognized in Japan. We herein report two cases of Japanese FMF patients who were diagnosed by genetic testing for the MEFV gene during the coro-navirus disease 2019 (COVID-19) pandemic. Both patients presented with symptoms similar to COVID-19, which delayed the definitive diagnosis. Patients with a confirmed diagnosis of FMF may be eligible for physical, emotional, and financial benefits. Therefore, the COVID-19 pandemic highlights the importance of differentiating the diagnosis by genetic testing.

引用

页码：643 / 647

页数：5

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