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RETRACTED: Serum bilirubin levels in primary Sjogren's syndrome: an association with interstitial lung disease (Retracted Article)
被引:1
作者:
Peng, You-Fan
[1
]
Lu, Fei-Yan
[2
]
Ma, Li-Ya
[1
]
机构:
[1] Youjiang Med Univ Nationalities, Affiliated Hosp, Dept Resp & Crit Care Med, 18 Zhongshan Er Rd, Baise 533000, Guangxi, Peoples R China
[2] Youjiang Med Univ Nationalities, Affiliated Hosp, Clin Pathol Diag & Res Ctr, Baise 533000, Peoples R China
关键词:
Serum bilirubin;
Primary Sjogren's syndrome;
Interstitial lung disease;
ANTIOXIDANT;
D O I:
10.1186/s12890-023-02672-5
中图分类号:
R56 [呼吸系及胸部疾病];
学科分类号:
摘要:
ObjectiveWe aimed to assess the association between serum bilirubin levels and interstitial lung disease (ILD) in patients with Primary Sjogren's syndrome (pSS).Materials and methodsThe retrospectively analysis included 89 consecutive patients with pSS, we collected the clinical materials of pSS patients from the electronic medical records, and all pSS patients were divide into pSS with ILD group and pSS without ILD group.ResultsSerum bilirubin levels were significantly lower in pSS patients with ILD than those without ILD (p = 0.010). Serum bilirubin levels showed a significant negative correlation with erythrocyte sedimentation rate (ESR) (r = -0.321, p = 0.002) in patients with pSS. A multivariable logistic regression analysis confirmed that serum bilirubin presented an independent association with ILD in patients with pSS (OR = 0.841, 95%CI:0.728-0.972, p = 0.019).ConclusionSerum bilirubin is independently associated with ILD and therefore may be a promising marker of ILD in patients with pSS.
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