A prospective study on the wound healing and quality of life outcomes of patients with venous leg ulcers in Singapore-Interim analysis at 6 month follow up

被引：6

作者：

Chan, Kai Siang ^{[1
]}

Lo, Zhiwen Joseph ^{[2
]}

Wang, Zifei ^{[3
]}

Bishnoi, Priya ^{[3
]}

Ng, Yi Zhen ^{[3
]}

Chew, Stacy ^{[3
]}

Chong, Tze Tec ^{[4
]}

Carmody, David ^{[5
]}

Ang, Shin Yuh ^{[6
]}

Yong, Enming ^{[1
]}

Chan, Yam Meng ^{[1
]}

Ho, Jackie ^{[7
]}

Graves, Nicholas ^{[8
]}

Harding, Keith ^{[3
]}

机构：

[1] Tan Tock Seng Hosp, Dept Gen Surg, Singapore, Singapore

[2] Woodlands Hlth, Dept Surg, 2 Yishun Cent 2, Singapore 76802, Singapore

[3] ASTAR, Skin Res Inst Singapore, Singapore, Singapore

[4] Singapore Gen Hosp, Dept Vasc Surg, Singapore, Singapore

[5] Singapore Gen Hosp, Dept Endocrinol, Singapore, Singapore

[6] Singapore Gen Hosp, Nursing Div, Singapore, Singapore

[7] Natl Univ Singapore Hosp, Dept Cardiac Thorac & Vasc Surg, Singapore, Singapore

[8] Duke NUS Med Sch, Hlth Serv & Syst Res, Singapore, Singapore

来源：

INTERNATIONAL WOUND JOURNAL | 2023年 / 20卷 / 07期

关键词：

chronic venous insufficiency; quality of life; venous leg ulcer; wound healing; INSUFFICIENCY; MANAGEMENT; ULCERATION; DISEASE; SCALE; PUSH;

D O I：

10.1111/iwj.14132

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Venous leg ulceration results in significant morbidity. However, the majority of studies conducted are on Western populations. This study aims to evaluate the wound healing and quality of life for patients with venous leg ulcers (VLUs) in a Southeast Asian population. This is a multi-centre prospective cohort study from Nov 2019 to Nov 2021. All patients were started on 2- or 4-layer compression bandage and were reviewed weekly or fortnightly. Our outcomes were wound healing, factors predictive of wound healing and the EuroQol 5-dimensional 5-level (EQ-5D-5L) health states. Within our cohort, there were 255 patients with VLU. Mean age was 65.2 +/- 11.6 years. Incidence of diabetes mellitus was 42.0%. Median duration of ulcer at baseline was 0.30 years (interquartile range 0.136-0.834). Overall, the median time to wound healing was 4.5 months (95% confidence interval [CI]: 3.77-5.43). The incidence of complete wound healing at 3- and 6-month was 47.0% and 60.9%, respectively. The duration of the wound at baseline was independently associated with worse wound healing (Hazard ratio 0.94, 95% CI: 0.89-0.99, P = .014). Patients with healed VLU had a significantly higher incidence of perfect EQ-5D-5L health states at 6 months (57.8% vs 13.8%, P < .001). We intend to present longer term results in subsequent publications.

引用

页码：2608 / 2617

页数：10