Cancer risk among HIV-exposed uninfected children in the United States

被引：0

作者：

Horner, Marie-Josephe ^{[1
]}

Hazra, Rohan ^{[2
]}

Barnholtz-Sloan, Jill S. ^{[1
,3
]}

Shiels, Meredith S. ^{[1
]}

Engels, Eric A. ^{[1
]}

机构：

[1] NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA

[2] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Div Extramural Res, Bethesda, MD USA

[3] NCI, Ctr Biomed Informat & Informat Technol, Bethesda, MD 20892 USA

来源：

AIDS | 2023年 / 37卷 / 03期

关键词：

TRANSMISSION;

D O I：

10.1097/QAD.0000000000003458

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In utero exposure to didanosine was associated with increased risk of brain cancer in a French study. We used United States health department records to assess cancer risk among 13 617 children exposed to HIV in utero, who remained HIV-uninfected after birth (1990-2017). Risk of brain tumors was borderline elevated among these children (standardized incidence ratio 2.2, 95% confidence interval 0.8-4.8, P=0.12, based on six cases). Risk was not significantly increased for leukemia or other cancers.

引用

页码：549 / 551

页数：3

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