Cancer risk among HIV-exposed uninfected children in the United States

被引：0
|
作者：
Horner, Marie-Josephe [1 ]
Hazra, Rohan [2 ]
Barnholtz-Sloan, Jill S. [1 ,3 ]
Shiels, Meredith S. [1 ]
Engels, Eric A. [1 ]
机构：
[1] NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
[2] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Div Extramural Res, Bethesda, MD USA
[3] NCI, Ctr Biomed Informat & Informat Technol, Bethesda, MD 20892 USA
来源：
AIDS | 2023年 / 37卷 / 03期
关键词：
TRANSMISSION;
D O I：
10.1097/QAD.0000000000003458
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In utero exposure to didanosine was associated with increased risk of brain cancer in a French study. We used United States health department records to assess cancer risk among 13 617 children exposed to HIV in utero, who remained HIV-uninfected after birth (1990-2017). Risk of brain tumors was borderline elevated among these children (standardized incidence ratio 2.2, 95% confidence interval 0.8-4.8, P=0.12, based on six cases). Risk was not significantly increased for leukemia or other cancers.
引用
收藏
页码：549 / 551
页数：3
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