Local Anesthetic Hypersensitivity Reactions in Pediatric Patients: Recognition and Management

被引:0
作者
Franceschini, Fabrizio [1 ]
Bottau, Paolo [1 ]
Caimmi, Silvia [2 ]
Bianchi, Annamaria [3 ]
Crisafulli, Giuseppe [4 ]
Liotti, Lucia [5 ]
Mori, Francesca [6 ]
Riscassi, Sara [7 ]
Saretta, Francesca [8 ]
Valluzzi, Rocco Luigi [9 ]
Caffarelli, Carlo [10 ]
机构
[1] Imola Hosp, Pediat & Neonatol Unit, I-40026 Imola, Italy
[2] Univ Pavia, San Matteo Hosp, Clin Pediat Unit, I-27100 Pavia, Italy
[3] San Camillo Forlanini Hosp, Pediat Unit, I-00152 Rome, Italy
[4] Univ Messina, Pediat Dept, Allergol Unit, I-98122 Messina, Italy
[5] Salesi Hosp, Pediat Unit, I-60100 Ancona, Italy
[6] Meyer Childrens Hosp, Allergy Unit, I-50139 Florence, Italy
[7] Bolzano Hosp, Pediat Dept, I-39100 Bolzano, Italy
[8] Univ Friuli Cent, Latisana Palmanova Hosp, Pediat Dept, Pediat Unit,Azienda Sanit, I-33100 Udine, Italy
[9] Bambino Gesu Pediatr Hosp, Pediat Dept, Allergol Unit, I-00165 Rome, Italy
[10] Univ Parma, Dept Med & Surg, Clin Pediat Unit, I-43126 Parma, Italy
关键词
drug adverse reactions; local anesthetic allergy; drug allergy; ALLERGIC CONTACT-DERMATITIS; ADVERSE-REACTIONS; CROSS-REACTIVITY; PHARMACOVIGILANCE; RISK; PROPOSAL; CHILDREN;
D O I
10.24976/Discov.Med.202436180.2
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Local anesthetics (LAs) are commonly used in all medical specialties, particularly in association with surgery, obstetrics, dentistry, and emergency departments. Most individuals, starting from young children, are exposed to LAs during life. LA hardly induces adverse events when used in recommended doses and with proper injection techniques. However, immediate anaphylactic reactions to LA injections may be a rare but life-threatening manifestation. A comprehensive report of the event and performing a specialist examination are crucial to prevent further episodes. The diagnosis should be based on history, medical records, skin and challenge tests.
引用
收藏
页码:16 / 21
页数:6
相关论文
共 38 条
[1]   Lidocaine: A Local Anesthetic, Its Adverse Effects and Management [J].
Bahar, Entaz ;
Yoon, Hyonok .
MEDICINA-LITHUANIA, 2021, 57 (08)
[2]   Adverse reactions and alleged allergy to local anesthetics: Analysis of 331 patients [J].
Batinac, Tanja ;
Sotosek Tokmadzic, Vlatka ;
Peharda, Vesna ;
Brajac, Ines .
JOURNAL OF DERMATOLOGY, 2013, 40 (07) :522-527
[3]   IgE-mediated allergy to local anaesthetics: separating fact from perception: a UK perspective [J].
Bhole, M. V. ;
Manson, A. L. ;
Seneviratne, S. L. ;
Misbah, S. A. .
BRITISH JOURNAL OF ANAESTHESIA, 2012, 108 (06) :903-911
[4]   Pharmacovigilance of drug allergy and hypersensitivity using the ENDA-DAHD database and the GA2LEN platform. The Galenda project [J].
Bousquet, P. -J. ;
Demoly, P. ;
Romano, A. ;
Aberer, W. ;
Bircher, A. ;
Blanca, M. ;
Brockow, K. ;
Pichler, W. ;
Torres, M. J. ;
Terreehorst, I. ;
Arnoux, B. ;
Atanaskovic-Markovic, M. ;
Barbaud, A. ;
Bijl, A. ;
Bonadonna, P. ;
Burney, P. G. ;
Caimmi, S. ;
Canonica, G. W. ;
Cernadas, J. ;
Dahlen, B. ;
Daures, J. -P. ;
Fernandez, J. ;
Gomes, E. ;
Gueant, J. -L. ;
Kowalski, M. L. ;
Kvedariene, V. ;
Mertes, P. -M. ;
Martins, P. ;
Nizankowska-Mogilnicka, E. ;
Papadopoulos, N. ;
Ponvert, C. ;
Pirmohamed, M. ;
Ring, J. ;
Salapatas, M. ;
Sanz, M. L. ;
Szczeklik, A. ;
Van Ganse, E. ;
De Weck, A. L. ;
Zuberbier, T. ;
Merk, H. F. ;
Sachs, B. ;
Sidoroff, A. .
ALLERGY, 2009, 64 (02) :194-203
[5]   Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs [J].
Broyles, Ana Dioun ;
Banerji, Aleena ;
Barmettler, Sara ;
Biggs, Catherine M. ;
Blumenthal, Kimberly ;
Brennan, Patrick J. ;
Breslow, Rebecca G. ;
Brockow, Knut ;
Buchheit, Kathleen M. ;
Cahill, Katherine N. ;
Cernadas, Josefina ;
Chiriac, Anca Mirela ;
Crestani, Elena ;
Demoly, Pascal ;
Dewachter, Pascale ;
Dilley, Meredith ;
Farmer, Jocelyn R. ;
Foer, Dinah ;
Fried, Ari J. ;
Garon, Sarah L. ;
Giannetti, Matthew P. ;
Hepner, David L. ;
Hong, David I. ;
Hsu, Joyce T. ;
Kothari, Parul H. ;
Kyin, Timothy ;
Lax, Timothy ;
Lee, Min Jung ;
Lee-Sarwar, Kathleen ;
Liu, Anne ;
Logsdon, Stephanie ;
Louisias, Margee ;
MacGinnitie, Andrew ;
Maciag, Michelle ;
Minnicozzi, Samantha ;
Norton, Allison E. ;
Otani, Iris M. ;
Park, Miguel ;
Patil, Sarita ;
Phillips, Elizabeth J. ;
Picard, Matthieu ;
Platt, Craig D. ;
Rachid, Rima ;
Rodriguez, Tito ;
Romano, Antonino ;
Stone, Cosby A., Jr. ;
Torres, Maria Jose ;
Verdu, Miriam ;
Wang, Alberta L. ;
Wickner, Paige .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2020, 8 (09) :S16-S116
[6]   Excipients in Anesthesia Medications [J].
Burbridge, Mark A. ;
Jaffe, Richard A. .
ANESTHESIA AND ANALGESIA, 2019, 128 (05) :891-900
[7]   Differences in local anaesthetic and antiepileptic binding in the inactivated state of human sodium channel Nav1.4 [J].
Buyan, Amanda ;
Whitfield, Aidan A. ;
Corry, Ben .
BIOPHYSICAL JOURNAL, 2021, 120 (24) :5553-5563
[8]   Approach to allergic contact dermatitis caused by topical medicaments [J].
Choi, Charles ;
Vafaei-Nodeh, Saba ;
Phillips, Jamie ;
de Gannes, Gillian .
CANADIAN FAMILY PHYSICIAN, 2021, 67 (06) :414-419
[9]   Delayed-type allergy to articaine with cross-reactivity to other local anesthetics from the amide group [J].
De Pasquale, Tiziana Maria Angela ;
Buonomo, Alessandro ;
Pucci, Stefano .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2018, 6 (01) :305-306
[10]   Safety of local anesthetics [J].
Figueiredo Pereira Cherobin, Ana Carolina ;
Tavares, Glaysson Tassara .
ANAIS BRASILEIROS DE DERMATOLOGIA, 2020, 95 (01) :82-90