Targeting the innate immune system to block acute inflammatory responses and increase AAV viral transduction of skeletal muscle in mdx mice

被引:0
|
作者
Morales, M. [1 ]
Spathis, R. [1 ]
Narvesen, S. [1 ]
Kuriplach, D. [1 ]
Huang, K. [1 ]
Bagley, E. [1 ]
Eybs, M. [1 ]
King, M. [1 ]
Sundar, T. [1 ]
Shulman, D. [1 ]
MacKinnon, A. [2 ]
Lawlor, M. [3 ]
Nagaraju, K. [1 ]
机构
[1] SUNY Binghamton, Sch Pharm & Pharmaceut Sci, Binghamton, NY USA
[2] AGADA Biosci Inc, Halifax, NS, Canada
[3] Div Translat Sci Lab, Milwaukee, WI USA
关键词
D O I
10.1016/j.nmd.2023.07.326
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
P263
引用
收藏
页码:S148 / S148
页数:1
相关论文
共 4 条
  • [1] Therapeutics targeting innate immune/inflammatory responses through the interleukin-6/JAK/STAT signal transduction pathway in patients with cancer
    Roxburgh, Campbell S. D.
    McMillan, Donald C.
    TRANSLATIONAL RESEARCH, 2016, 167 (01) : 61 - 66
  • [2] Cysteamine-mediated blockade of the glycine cleavage system modulates epithelial cell inflammatory and innate immune responses to viral infection
    Fraser-Pitt, Douglas
    Mercer, Derry K.
    Francis, Marie-Louise
    Toledo-Aparicio, David
    Smith, Daniel W.
    O'Neil, Deborah A.
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 677 : 168 - 181
  • [3] Ischemic Preconditioning Modulates the Peripheral Innate Immune System to Promote Anti-Inflammatory and Protective Responses in Mice Subjected to Focal Cerebral Ischemia
    Amantea, Diana
    La Russa, Daniele
    Frisina, Marialaura
    Giordano, Francesca
    Di Santo, Chiara
    Panno, Maria Luisa
    Pignataro, Giuseppe
    Bagetta, Giacinto
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [4] Immune system regulation of transgene expression in the brain 2: Differential increase of mRNAs encoding for interferon-regulated, chemokine, and T-cell genes during either innate acute or chronic systemic adaptive immune responses to first generation adenoviral vectors
    Zirger, JM
    Barcia, C
    Liu, CY
    Puntel, M
    Sitia, G
    Guidotti, L
    Mitchell, N
    Campbell, I
    Castro, MG
    Lowenstein, PR
    MOLECULAR THERAPY, 2004, 9 : S390 - S391