Identifying Effective Durations of Antibiotic Therapy for the Treatment of Carbapenem-resistant Enterobacterales Bloodstream Infections: A Multicenter Observational Study

被引：8
作者：
Soto, Caitlin L. [1 ]
Hsu, Alice J. [1 ]
Lee, Jae Hyoung [2 ]
Dzintars, Kathryn [1 ]
Choudhury, Rebecca [3 ]
Jenkins, Timothy C. [4 ]
Mccreary, Erin K. [5 ]
Quartuccio, Katelyn S. [6 ]
Stohs, Erica J. [7 ]
Zimmerman, Matty [1 ]
Tamma, Pranita D. [2 ,8 ]
机构：
[1] Johns Hopkins Univ Hosp, Dept Pharm, Baltimore, MD USA
[2] Johns Hopkins Univ, Dept Pediat, Baltimore, MD 21287 USA
[3] Montefiore Med Ctr, Dept Med, Bronx, NY USA
[4] Denver Hlth, Dept Med, Denver, CO USA
[5] Univ Pittsburgh, Dept Med, Sch Med, Pittsburgh, PA USA
[6] Univ Rochester, Med Ctr, Dept Pharm, Rochester, NY 14627 USA
[7] Univ Nebraska, Dept Med, Med Ctr, Omaha, NE USA
[8] Johns Hopkins Univ, Dept Pediat, Sch Med, 200 North Wolfe St,Rubinstein Bldg,Rm 3149, Baltimore, MD 21287 USA
来源：
CLINICAL INFECTIOUS DISEASES | 2024年 / 78卷 / 01期
关键词：
carbapenem-resistant Enterobacterales; bacteremia; ceftazidime-avibactam; meropenem-vaborbactam;
D O I：
10.1093/cid/ciad476
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In a propensity-score-weighted cohort of 183 adults with carbapenem-resistant Enterobacterales bacteremia at 24 US hospitals, patients receiving short courses of active therapy (7-10 days, median 9 days) experienced similar odds of recurrent bacteremia or death within 30 days as those receiving prolonged courses of active therapy (14-21 days, median 14 days).
引用
收藏
页码：27 / 30
页数：4
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