Identifying Effective Durations of Antibiotic Therapy for the Treatment of Carbapenem-resistant Enterobacterales Bloodstream Infections: A Multicenter Observational Study

被引：7

作者：

Soto, Caitlin L. ^{[1
]}

Hsu, Alice J. ^{[1
]}

Lee, Jae Hyoung ^{[2
]}

Dzintars, Kathryn ^{[1
]}

Choudhury, Rebecca ^{[3
]}

Jenkins, Timothy C. ^{[4
]}

Mccreary, Erin K. ^{[5
]}

Quartuccio, Katelyn S. ^{[6
]}

Stohs, Erica J. ^{[7
]}

Zimmerman, Matty ^{[1
]}

Tamma, Pranita D. ^{[2
,8
]}

机构：

[1] Johns Hopkins Univ Hosp, Dept Pharm, Baltimore, MD USA

[2] Johns Hopkins Univ, Dept Pediat, Baltimore, MD 21287 USA

[3] Montefiore Med Ctr, Dept Med, Bronx, NY USA

[4] Denver Hlth, Dept Med, Denver, CO USA

[5] Univ Pittsburgh, Dept Med, Sch Med, Pittsburgh, PA USA

[6] Univ Rochester, Med Ctr, Dept Pharm, Rochester, NY 14627 USA

[7] Univ Nebraska, Dept Med, Med Ctr, Omaha, NE USA

[8] Johns Hopkins Univ, Dept Pediat, Sch Med, 200 North Wolfe St,Rubinstein Bldg,Rm 3149, Baltimore, MD 21287 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2024年 / 78卷 / 01期

关键词：

carbapenem-resistant Enterobacterales; bacteremia; ceftazidime-avibactam; meropenem-vaborbactam;

D O I：

10.1093/cid/ciad476

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In a propensity-score-weighted cohort of 183 adults with carbapenem-resistant Enterobacterales bacteremia at 24 US hospitals, patients receiving short courses of active therapy (7-10 days, median 9 days) experienced similar odds of recurrent bacteremia or death within 30 days as those receiving prolonged courses of active therapy (14-21 days, median 14 days).

引用

页码：27 / 30

页数：4

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