p-TSA Catalyzed One-Pot Synthesis of 2-(1H-Indol-3-yl)-3-Phenylquinazolin-4(3H)-Ones

被引：5

作者：

Tamilselvi, Velmurugan ^{[1
]}

Ramesh, Rathinam ^{[2
]}

Lalitha, Appaswami ^{[1
]}

机构：

[1] Periyar Univ, Dept Chem, Salem 636011, Tamil Nadu, India

[2] Sona Coll Arts & Sci, Dept Chem, Salem, Tamil Nadu, India

来源：

POLYCYCLIC AROMATIC COMPOUNDS | 2023年 / 43卷 / 01期

关键词：

p-TSA; 2-(1H-indol-3-yl)-3-phenylquinazolin-4(3H)-ones; one-pot; multicomponent; MEDICINAL SCAFFOLDS; DERIVATIVES; QUINAZOLINONE; ANTICANCER; EFFICIENT;

D O I：

10.1080/10406638.2021.2015399

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Herein, we wish to report a p-TSA catalyzed synthesis of a new series of 2-(1H-indol-3-yl)-3-phenylquinazolin-4(3H)-ones in methanol at reflux condition. The present protocol has the advantages of simple work up, high yield with shorter reaction time, inexpensive catalyst, easily available starting materials and no need of chromatographic purification. The products were characterized by various spectral techniques.

引用

页码：434 / 443

页数：10

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