Multisystem inflammatory syndrome in adults: Characteristics, treatment, and outcomes

被引：10

作者：

Lai, Chih-Cheng ^{[1
]}

Hsu, Chi-Kuei ^{[2
]}

Hsueh, Shun-Chung ^{[3
]}

Yen, Muh-Yong ^{[4
]}

Ko, Wen-Chien ^{[5
,6
]}

Hsueh, Po-Ren ^{[7
,8
,9
,10
,11
,12
]}

机构：

[1] Chi Mei Med Ctr, Div Hosp Med, Dept Internal Med, Tainan, Taiwan

[2] E Da Hosp, Dept Internal Med, Kaohsiung, Taiwan

[3] Natl Taiwan Univ Hosp, Dept Internal Med, Taipei, Taiwan

[4] Natl Yang Ming Chiao Tung Univ, Cheng Hsin Gen Hosp, Sch Med, Div Infect Dis, Taipei, Taiwan

[5] Natl Cheng Kung Univ, Natl Cheng Kung Univ Hosp, Coll Med, Dept Internal Med, Tainan, Taiwan

[6] Natl Cheng Kung Univ, Coll Med, Dept Med, Tainan, Taiwan

[7] China Med Univ Hosp, Dept Lab Med, Taichung, Taiwan

[8] China Med Univ Hosp, Dept Internal Med, Taichung, Taiwan

[9] China Med Univ, Sch Med, Taichung, Taiwan

[10] Natl Taiwan Univ Hosp, Natl Taiwan Univ Coll Med, Dept Lab Med, Taipei, Taiwan

[11] China Med Univ, China Med Univ Hosp, Dept Lab Med, 2, Yude Rd, Taichung 40447, Taiwan

[12] China Med Univ, China Med Univ Hosp, Dept Internal Med, 2, Yude Rd, Taichung 40447, Taiwan

来源：

JOURNAL OF MEDICAL VIROLOGY | 2023年 / 95卷 / 02期

关键词：

adults; COVID-19; multisystem inflammatory syndrome; SARS-CoV-2; COVID-19;

D O I：

10.1002/jmv.28426

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Following the rapidly increasing number of multisystem inflammatory syndromes in children (MIS-C), a similar clinical scenario has been observed in adult patients. Although its prevalence is low and probably related to underdiagnosis, its development can be associated with high mortality. Multisystem inflammatory syndrome in adults (MIS-A) can develop following both asymptomatic and symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and in previously healthy people. Like MIS-C, MIS-A is a multisystem disease that can involve the cardiovascular, respiratory, gastrointestinal, dermatologic, hematologic, and neurologic systems. In addition to the clinical manifestations, the diagnosis of MIS-A requires laboratory evidence of inflammation and SARS-CoV-2 infection. The appropriate treatment for MIS-A remains unclear; anti-inflammatory agents, including intravenous immunoglobulin and corticosteroids, are commonly used. However, there are still many unknowns regarding MIS-A. Further studies are needed to determine the true prevalence, pathogenesis, and effective treatment for MIS-A.

引用

页数：9

共 74 条

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