Exploring the trajectory curve of long-term musculoskeletal post-COVID pain symptoms in hospitalized COVID-19 survivors: a multicenter study

被引：21

作者：

Fernandez-de-las-Penas, Cesar ^{[1
,2
]}

Cancela-Cilleruelo, Ignacio ^{[1
]}

Moro-Lopez-Menchero, Paloma ^{[1
]}

Rodriguez-Jimenez, Jorge ^{[1
]}

Pellicer-Valero, Oscar J. ^{[3
]}

Martin-Guerrero, Jose D. ^{[3
]}

Arendt-Nielsen, Lars ^{[2
,4
]}

机构：

[1] Univ Rey Juan Carlos URJC, Dept Phys Therapy Occupat Therapy Phys Med & Reha, Madrid, Spain

[2] Aalborg Univ, Fac Med, Ctr Neuroplast & Pain CNAP, Dept Hlth Sci & Technol,SMI, Aalborg, Denmark

[3] Univ Valencia UV, Engn Sch, Dept Elect Engn, Intelligent Data Anal Lab, Valencia, Spain

[4] Aalborg Univ Hosp, Dept Med Gastroenterol Mech Sense, Aalborg, Denmark

来源：

PAIN | 2023年 / 164卷 / 02期

基金：

新加坡国家研究基金会;

关键词：

COVID-19; Musculoskeletal pain; Post-COVID; Risk factors; Prevalence; INCREASE; ANXIETY;

D O I：

10.1097/j.pain.0000000000002718

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

This multicenter cohort study investigated the prevalence of musculoskeletal post-COVID pain during the first year after the infection with mosaic plots and an exponential bar plot model and its associated risk factors. Patients hospitalized because of COVID-19 in 5 hospitals of Madrid (Spain) were scheduled for a telephone interview at 2 follow-up periods after hospitalization for collecting data about musculoskeletal post-COVID pain. Hospitalization and clinical data were collected from hospital medical records. From 2000 patients initially recruited, 1593 (44.6% women, age: 61 +/- 15 years) were assessed at T0 (hospital admission), T1 (mean: 8.0 +/- 1.5 months after discharge), and T2 (mean: 13.2 +/- 1.5 months after discharge). The prevalence of musculoskeletal pain (myalgia) was 30.3% (n = 483) at T0, increased to 43.4% (n = 692) at T1, and decreased to 37.8% (n = 603) at T2. The trajectory curve revealed a decreasing prevalence trend of musculoskeletal post-COVID pain the following years after hospitalization. According to the presence of pre-existing pain symptoms, the prevalence of new-onset post-COVID pain was 75.9%. Female sex (odds ratio [OR] 1.593, 95% confidence interval [CI] 1.148-2.211), history of musculoskeletal pain (OR 1.591, 95% CI 1.211-2.07), the presence of myalgia (OR 1.371, 95% CI 1.032-1.821) or headache (OR 2.278, 95% CI 1.622-3.199) at hospitalization, the days of hospitalization (OR 1.013, 95% CI 1.000-1.025), and the presence of post-COVID pain at T1 (OR 11.02, 95% CI 8.493-14.305) were factors associated with musculoskeletal post-COVID pain 1 year after hospitalization. In conclusion, musculoskeletal post-COVID pain remains highly prevalent 1 year after hospitalization. Female sex, previous history of pain symptoms, pain symptoms at onset, and days at hospital were factors associated with musculoskeletal post-COVID pain 1 year after hospitalization.

引用

页码：413 / 420

页数：8

共 34 条

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