Breast implant-associated squamous cell carcinoma: an evidence-based systematic review

被引：4

作者：

Pagliara, Domenico ^{[1
]}

Grieco, Federica ^{[2
]}

Cuomo, Roberto ^{[3
]}

Schiavone, Laurenza ^{[4
]}

Boriani, Filippo ^{[5
]}

Figus, Andrea ^{[5
]}

Atzeni, Matteo ^{[5
]}

Ribuffo, Diego ^{[4
]}

Salgarello, Marzia ^{[6
]}

Rubino, Corrado ^{[2
]}

机构：

[1] Mater Olbia Hosp, Plast Reconstruct & Lymphedema Microsurg Ctr, Str Statale 125 Orientale Sarda, I-07026 Olbia, Italy

[2] Univ Sassari, Sassari Univ Hosp Trust, Dept Med Surg & Expt Sci, Plast Reconstruct & Aesthet Surg Unit, Viale S Pietro 43, I-07100 Sassari, Italy

[3] Univ Siena, Dept Med Surg & Neurosci, Plast & Reconstruct Surg Unit, I-53100 Siena, Italy

[4] Sapienza Univ Rome, Dept Surg P Valdoni, Unit Plast & Reconstruct Surg, Policlin Umberto I, Via Ettore Fieramosca 200, I-00159 Rome, Italy

[5] Univ Cagliari, Univ Hosp Duilio Casula, Fac Med & Surg, Dept Surg Sci,Plast Surg & Microsurg Unit, SS554,4, I-09042 Monserrato, Italy

[6] IRCCS A Gemelli Univ Polyclin Fdn, Dept Woman & Child Hlth & Publ Hlth, Largo A Gemelli 8, I-00168 Rome, Italy

来源：

EUROPEAN JOURNAL OF PLASTIC SURGERY | 2023年 / 46卷 / 06期

关键词：

Squamous cell carcinoma; Breast implant; Breast implant capsule; Breast implant capsule-associated squamous cell carcinoma; BIA-SCC; Breast implant associated malignancies; CAPSULE; REVISION; LYMPHOMA; SILICONE;

D O I：

10.1007/s00238-023-02078-w

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

BackgroundWith the recent safety communication issued by The Food and Drug Administration, squamous cell carcinoma breast-implant associated (BIA-SCC) has become part of the breast implant capsule related conditions. In the present paper, we review all cases of BIA-SCC currently reported in the literature.MethodsFrom October 2022 to February 2023, we conducted a systematic review of the literature in accordance with the Preferred Reporting Items for Systematic Reviews and Meta Analyses (PRISMA) statement. An electronic search was performed using PubMed/Medline, Scopus, and Cochrane Database. Only manuscripts written in English and featuring one or more clinical cases of BIA-SCC were included for full-text analysis.ResultsEight-hundred-sixty-seven articles were identified. After excluding duplicates, irrelevant and non-English-written papers, fifteen articles were deemed eligible for the review, featuring a total of eighteen cases. Eleven patients received bilateral breast augmentation, five bilateral or unilateral reconstruction either following mastectomy or for Poland syndrome, while in two cases the indication for implant placement was not reported. Time from implantation to clinical onset was less than ten years in three patients, over ten years in thirteen instances and not reported in two. History of capsular contracture was identified in eight patients, while complications including previous surgical revisions, implant exchange or exposure, extrusion or infection were reported in eight cases.ConclusionsThe paucity of literature on BIA-SCC still hinders us from drawing definitive conclusions. Nevertheless, we can infer that early detection of symptoms is pivotal in the decision-making process for the treatment and management of this nosological entity.Level of evidence: Not gradable

引用

页码：875 / 886

页数：12

共 42 条

[1]

Alfaro L, 2019, VIRCHOWS ARCH, V475, pS64

[2] Squamous Metaplasia on the Breast Implant Capsule [J].