Hydroxyl-Directed Ru(II)-Catalyzed Synthesis of Fused Dihydrofurans Using 1,4-Dioxane and Sulfoxonium Ylides as Annulating Agents

被引：18
作者：
Phukon, Jyotshna [1 ,2 ]
Bhorali, Pratiksha [1 ,2 ]
Changmai, Sumi [1 ,2 ]
Gogoi, Sanjib [1 ,2 ]
机构：
[1] North East Inst Sci & Technol, Chem Sci & Technol Div, Appl Organ Chem, CSIR, Jorhat 785006, India
[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
来源：
ORGANIC LETTERS | 2023年 / 25卷 / 01期
关键词：
BOND;
D O I：
10.1021/acs.orglett.2c04068
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An unprecedented annulation reaction is developed for the synthesis of dihydrofuran-fused compounds. In this Ru-catalyzed hydroxyl-group-directed reaction, easily affordable sulfoxonium ylides and 1,4-dioxane were used as the annulating partners. This is the first example of the use of 1,4-dioxane as a methylene source to construct a heterocyclic scaffold. A wide range of dihydrofuran0fused coumarins and naphthalenes were synthesized using this three-component reaction.
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收藏
页码：215 / 219
页数：5
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