Epidemiology and early screening strategies for colorectal cancer in China

被引：6

作者：

Yang, Yong ^{[1
]}

Gao, Zhaoya ^{[1
]}

Huang, An ^{[2
]}

Shi, Jingyi ^{[2
]}

Sun, Zhuang ^{[2
]}

Hong, Haopeng ^{[2
]}

Gu, Jin ^{[1
,2
]}

机构：

[1] Peking Univ, Shougang Hosp, Dept Gastrointestinal Surg, Beijing 100144, Peoples R China

[2] Peking Univ, Canc Hosp & Inst, Gastrointestinal Canc Ctr,Minist Educ, Key Lab Carcinogenesis & Translat Res, Beijing 100142, Peoples R China

来源：

CHINESE JOURNAL OF CANCER RESEARCH | 2023年 / 35卷 / 06期

关键词：

Colorectal cancer; epidemiology; early screening; review; STOOL DNA; DIAGNOSTIC-ACCURACY; MORTALITY; RISK; POLYPECTOMY; GUIDELINES; TESTS; CRC;

D O I：

10.21147/j.issn.1000-9604.2023.06.05

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

China ranks the first worldwide in the number of new colorectal cancer (CRC) cases and CRC-related deaths. The increasing incidence of early-onset CRC in recent years highlights the challenges related to CRC screening and prevention. High-quality colonoscopy is the universally used gold standard for CRC screening. Risk assessment combined with a two-step screening strategy based on colonoscopy and non-invasive examinations was proven to be highly effective. However, systematic use of well-established risk factors associated with CRC, beyond age, could better identify those who might harbor advanced colorectal neoplasia, improve the diagnostic yield of current screening modalities, and optimize the selection of individuals who might benefit most from preventive strategies. "Personalization" and "Standardization" are the future development directions of CRC screening, from the initiation of screening in those at high risk for CRC to follow-up after treatment, which are the key to ensure the screening efficiency.

引用

页数：13