Transversus abdominis plane block versus caudal block with bupivacaine and dexmedetomidine for unilateral inguinal hernia repair in pediatric patients: a randomized clinical trial

被引:2
作者
Abo El Fadl, Ghada M. [1 ]
Osman, Hany M. [1 ]
Anwar, Mohamed [1 ]
Sabra, Tarek [2 ]
Ismael, Wael A. [3 ]
Abdelrady, Marwa M. [4 ]
机构
[1] Assiut Univ, Fac Med, Dept Anesthesia Intens Care & Pain Management, Assiut, Egypt
[2] Assiut Univ, Fac Med, Dept Pediat Surg, Assiut, Egypt
[3] Assiut Univ, Fac Med, Dept Ophthalmol, Assiut, Egypt
[4] New Valley Univ, Fac Med, Dept Anesthesia & Intens Care, New Valley, Egypt
关键词
Anesthesia; caudal; Dexmedetomidine; Ultrasonography; ROPIVACAINE; CHILDREN; CLONIDINE;
D O I
10.23736/S0375-9393.23.16675-2
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
BACKGROUND: This study compared the transversus abdominis plane (TAP) block with bupivacaine and dexmedeto-midine to the same mixture in the caudal block in delivering postoperative analgesia in children after unilateral inguinal hernia surgery. METHODS: The current study included 80 children aged two to eight years who were scheduled for unilateral inguinal hernia surgery under general anesthesia. A caudal block (1 mL/kg 0.25% bupivacaine and one mu g /kg dexmedetomidine) or a TAP block (1 mL/kg 0.25% bupivacaine and one mu g /kg dexmedetomidine) was given to each participant at random. The time it took to request analgesia for the first time, the postoperative pain score, total analgesic use, sedation, family satisfaction, and side effects were all measured. The primary outcome was time to first analgesic request. RESULTS: The caudal block group had a considerably shorter time to first analgesic request than the TAP block group. The caudal block group received more rescue analgesia doses within 24 hours than the TAP block group. The mean total dose of intravenous paracetamol within the first 24 hours postoperatively was greater in the caudal block group. The caudal block group had much higher family satisfaction. CONCLUSIONS: The TAP block and caudal block provide good postoperative analgesia in children undergoing uni-lateral inguinal hernia repair. Adding dexmedetomidine to the TAP block was superior to the caudal block in terms of extending the length of the initial analgesic request, lowering analgesic requirement, and lowering pain scores without causing substantial adverse effects.
引用
收藏
页码:744 / 752
页数:9
相关论文
共 30 条
[1]   Ultrasound guided TAP block versus ultrasound guided caudal block for pain relief in children undergoing lower abdominal surgeries [J].
Alsadek, Wafaa Mohamed ;
Al-Gohari, Manal Mohamed ;
Elsonbaty, Mohamad Ibrahim ;
Nassar, Heba Mohamed ;
Alkonaiesy, Ramy Mohamed .
EGYPTIAN JOURNAL OF ANAESTHESIA, 2015, 31 (02) :155-160
[2]   The Analgesic Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block in Adult Patients: A Meta-Analysis [J].
Baeriswyl, Moira ;
Kirkham, Kyle R. ;
Kern, Christian ;
Albrecht, Eric .
ANESTHESIA AND ANALGESIA, 2015, 121 (06) :1640-1654
[3]   The locus coeruleus-noradrenergic system: modulation of behavioral state and state-dependent cognitive processes [J].
Berridge, CW ;
Waterhouse, BD .
BRAIN RESEARCH REVIEWS, 2003, 42 (01) :33-84
[4]  
Bonnet F, 2009, Transversus abdominis plane block: what is its role in postoperative analgesia?
[5]   Ultrasound assessment of cranial spread during caudal blockade in children: the effect of different volumes of local anaesthetics [J].
Brenner, L. ;
Marhofer, P. ;
Kettner, S. C. ;
Willschke, H. ;
Machata, A. -M. ;
Al-Zoraigi, U. ;
Lundblad, M. ;
Lonnqvist, P. -A. .
BRITISH JOURNAL OF ANAESTHESIA, 2011, 107 (02) :229-235
[6]   Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat [J].
Brummett, Chad M. ;
Norat, Mary A. ;
Palmisano, John M. ;
Lydic, Ralph .
ANESTHESIOLOGY, 2008, 109 (03) :502-511
[7]   The Transversus Abdominis Plane Block Provides Effective Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy [J].
Carney, John ;
McDonnell, John G. ;
Ochana, Alan ;
Bhinder, Raj ;
Laffey, John G. .
ANESTHESIA AND ANALGESIA, 2008, 107 (06) :2056-2060
[8]   Effect of Adding Dexmedetomidine to Ropivacaine on Ultrasound-Guided Dual Transversus Abdominis Plane Block after Gastrectomy [J].
Ding, Wengang ;
Li, Wanying ;
Zeng, Xianzhang ;
Li, Jinying ;
Jiang, Jingjing ;
Guo, Changchun ;
Li, Wenzhi .
JOURNAL OF GASTROINTESTINAL SURGERY, 2017, 21 (06) :936-946
[9]  
Ford A, 2014, SURG COMPLI RISKS, P25, DOI 10.1007/978-1-4471-5439-6_3
[10]   Early experience with the transversus abdominis plane block in children [J].
Fredrickson, Michael ;
Seal, Philippa ;
Houghton, James .
PEDIATRIC ANESTHESIA, 2008, 18 (09) :891-892