Retrospective evaluation of patients with intracranial bleeding due to late vitamin K deficiency Intracranial bleeding in Vitamin K deficiency

Aim: In this study, we share our clinical experience and raise awareness about the importance of vitamin K prophylaxis. We evaluated Material and Methods: We retrospectively evaluated the demographic characteristics, clinical and radiological findings of 9 patients with late vitamin K deficiency bleeding (VKDH) who were we followed in our clinic in 2020. Results: It was determined that none of the 9 patients received postpartum vitamin K prophylaxis. The mean admission international normalized ratio (INR) of the patients was 4.2+1.1. Vitamin K was administered to all patients, and the mean of INR values decreased to 1.1+0.1. The most common complaint of the patients was convulsion (77.8%). Subarachnoid hemorrhage (SAH) + subdural hemorrhage (SDH) were detected in 4 patients, SAH+SDH+intraparenchymal hemorrhage (IPH) in 3 patients, SAH+IPH in 1 patient, and SAH in 1 patient. Surgery was performed on 3 patients. Two patients who were not operated died during their intensive care follow-up. Seven patients were discharged. Hemiplegia developed in 2 patients, and these patients were included in the physical therapy program. Discussion: Late VKDB is most commonly seen between 2-12 weeks after birth. It causes serious morbidity and mortality. It is difficult to treat, time consuming and costly. It is possible to prevent late VKDB with intramuscular vitamin K prophylaxis after delivery.