In this paper, a novel technology, which is the thermal power generation (TEG)-organic Rankine cycle (ORC) combined cycle system, is proposed to recycle cascade utilisation of main engine waste heat. Evaporation pressure of working fluid (P) is an important parameter affecting the combined cycle, but its performance in the TEG-ORC combined cycle is unknown. Therefore, the TEG-ORC experimental device is built in this paper, and the environmentally friendly R245fa is employed to study the variation of the main parameters such as the system net power output (W-net), system thermal efficiency (?(s)), power-production cost (C-g), and waste heat utilisation of main engine flue gas (f(g)) under different evaporation pressure (P). When the P is 0.75 Mpa, the output performance of the system parameters is optimal. The W-net, ?(s), waste heat utilisation power (W-p), C-g, and rate of f(g), is 483.25 W, 8.34%, 5796.72 W, 0.3464 $ /kWh, and 69.05 %, respectively.