Investigation on maintenance hemodialysis patients with mineral and bone disorder in Anhui province, China

被引：1

作者：

Tao, Shuman ^{[1
]}

Li, Xiuyong ^{[2
]}

Liu, Zhi ^{[3
]}

Bai, Youwei ^{[4
]}

Qian, Guangrong ^{[5
]}

Wu, Han ^{[6
]}

Li, Ji ^{[7
]}

Guo, Yuwen ^{[8
]}

Yang, Shanfei ^{[9
]}

Chen, Lei ^{[10
]}

Yang, Jian ^{[11
]}

Han, Jiuhuai ^{[12
]}

Ma, Shengyin ^{[13
]}

Yang, Jing ^{[14
]}

Yu, Linfei ^{[15
]}

Shui, Runzhi ^{[16
]}

Jin, Xiping ^{[17
]}

Wang, Hongyu ^{[18
]}

Zhang, Fan ^{[19
]}

Chen, Tianhao ^{[20
]}

Li, Xinke ^{[21
]}

Zong, Xiaoying ^{[22
]}

Liu, Li ^{[23
]}

Fan, Jihui ^{[24
]}

Wang, Wei ^{[25
]}

Zhang, Yong ^{[26
]}

Shi, Guangcai ^{[27
]}

Wang, Deguang ^{[1
]}

机构：

[1] Anhui Med Univ, Dept Nephrol, Hosp 2, 678 Furong Rd, Hefei 230601, Peoples R China

[2] 2 Peoples Hosp Fuyang City, Blood Purificat Ctr, 1088 Yinghe West Rd, Fuyang 236015, Peoples R China

[3] Anhui Univ Sci & Technol, Dept Nephrol, Affiliated Hosp 1, 203 Huaibin Rd, Huainan 232000, Peoples R China

[4] Second Peoples Hosp Luan City, Dept Nephrol, 73 Mozitan Rd, Luan 237000, Peoples R China

[5] Maanshan Peoples Hosp, Dept Nephrol, 45 Hubei Rd, Maanshan 243099, Peoples R China

[6] Bozhou Peoples Hosp, Blood Purificat Ctr, 616 Duzhong Rd, Bozhou 236814, Peoples R China

[7] Tongling Peoples Hosp, Dept Nephrol, 468 Bijiashan Rd, Tongling 244099, Peoples R China

[8] Lujiang Cty Peoples Hosp, Dept Nephrol, 32 Wenmingzhong Rd, Lujiang 231501, Peoples R China

[9] Shouxian Cty Hosp, Dept Nephrol, Northeast Intersect Binyang Ave & Dongjin Ave, Huainan 232200, Shouxian County, Peoples R China

[10] Hefei Jinnan Kidney Hosp, Dept Nephrol, Northeast Intersect Fozhang Rd & Beihai Rd, Hefei 230071, Peoples R China

[11] Funan Cty Peoples Hosp, Dept Nephrol, 36 Santa Rd, Fuyang 236300, Funan County, Peoples R China

[12] Anqing Municipal Hosp, Dept Nephrol, 87 East Tianzhushan Rd, Anqing 246003, Peoples R China

[13] Anhui Wanbei Coal Elect Grp Gen Hosp, Dept Nephrol, 125 Huaihe West Rd, Suzhou 234099, Peoples R China

[14] First Peoples Hosp Hefei, Dept Nephrol, 390 Huaihe Rd, Hefei 230061, Peoples R China

[15] Peoples Hosp Taihu, Dept Nephrol, 196 Renmin Rd, Anqing 246400, Taihu County, Peoples R China

[16] Huangshan City Peoples Hosp, Blood Purificat Ctr, 4 Liyuan Rd, Huangshan 245000, Peoples R China

[17] Huainan Chao Yang Hosp, Dept Nephrol, 15 Renmin South Rd, Huainan 232007, Peoples R China

[18] Lixin Cty Peoples Hosp, Dept Nephrol, Intersect Wenzhou Rd & Feihe Rd, Bozhou 236700, Lixin County, Peoples R China

[19] Dongzhi Cty Peoples Hosp, Dept Nephrol, 70 Jianshe Rd, Chizhou 247299, Dongzhi County, Peoples R China

[20] Tianchang City Peoples Hosp, Dept Nephrol, 137 Jianshe East Rd, Tianchang 239399, Peoples R China

[21] Xiaoxian Peoples Hosp, Dept Nephrol, 58 Jiankang Rd, Suzhou 235200, Xiaoxian County, Peoples R China

[22] Bengbu Med Coll, Dept Nephrol, Affiliated Hosp 2, 633 Longhua Rd, Bengbu 233017, Peoples R China

[23] Second Peoples Hosp Hefei, Dept Nephrol, 246 Heping Rd, Hefei 230012, Peoples R China

[24] Huaibei Peoples Hosp, Dept Nephrol, 66 Huaihai West Rd, Huaibei 235000, Peoples R China

[25] Peoples Hosp Xuancheng City, Dept Nephrol, 51 Dabatang Rd, Xuancheng 242099, Peoples R China

[26] Lujiang Cty Hosp TCM, Dept Nephrol, 350 Zhouyu Ave, Lucheng Town 231501, Lujiang County, Peoples R China

[27] Fifth Peoples Hosp Hefei, Dept Nephrol, Yuxi Rd, Hefei 230011, Peoples R China

来源：

INTERNATIONAL UROLOGY AND NEPHROLOGY | 2023年 / 55卷 / 02期

关键词：

Chronic kidney disease; Hemodialysis; Mineral and bone disorder; 10-YEAR OUTCOMES; KIDNEY-DISEASE; PHOSPHATE; RISK; ASSOCIATION; MORTALITY; MARKERS; CALCIUM; DEATH;

D O I：

10.1007/s11255-022-03328-9

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Background Chronic kidney disease-mineral bone disorder (CKD-MBD) is a common comorbidity in patients with CKD. The study aims to describe the control rates of serum-corrected calcium (Ca), phosphate (P) and intact parathyroid hormone (iPTH) and its risk factors among maintenance hemodialysis (MHD) patients in Anhui Province of China. Methods The study was conducted in 27 hemodialysis centers of Anhui Province between January 1st 2020 and December 31th 2020. Chi-square test was used to compare the control rates of serum-corrected Ca, P and iPTH between the present study and DOPPS 4 or Anhui Province in 2014. Binary logistic regression analysis was used to explore the risk factors of the control rates of serum-corrected Ca, P and iPTH. Results A total of 3 025 MHD patients were recruited in this study, with a mean age of 54.8 (SD: 12.8) years, and 60.1% were males. According to the Chinese Diagnosis and Treatment Guidelines for CKD-MBD, the control rates of serum-corrected Ca, P and iPTH in the present study were 57.9%, 20.0% and 56.0%, respectively. Based on KDOQI guidelines (2003), the control rates of the above indicators were 43.1%, 35.3% and 22.3%, respectively. The control rates of serum-corrected Ca, P and iPTH in this study were lower than those of DOPPS 4 (P < 0.001). Compared to the results of Anhui Province in 2014, the control rate of corrected Ca was higher (P < 0.001) and the control rate of iPTH was lower (P = 0.005). Age, residential area, BMI, dialysis vintage, albumin and hemoglobin levels were factors of serum-corrected Ca, P and iPTH not within target range. Conclusion The control rates of serum-corrected Ca, P and iPTH in MHD patients in Anhui Province are relatively low. Monitoring and management should be strengthened to improve the prognosis of patients undergoing dialysis.

引用

页码：389 / 398

页数：10

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