Lock-in Amplifier Dairy Sensor for Detection of Ciprofloxacin

被引：2
作者：
Devasagayam, Jasen [1 ,2 ]
Leclerc, Camille A. [1 ,2 ]
Bosma, Rick [1 ,2 ]
Wood, Larry [3 ]
Collier, Christopher M. [1 ,2 ]
机构：
[1] Univ British Columbia, Fac Appl Sci, Sch Engn, Okanagan Campus, Kelowna, BC V1V 1V7, Canada
[2] Univ Guelph, Coll Engn & Phys Sci, Sch Engn, Guelph, ON N1G 2W1, Canada
[3] CG Wellington, Drayton, ON N0G 1P0, Canada
来源：
IEEE ACCESS | 2023年 / 11卷
关键词：
Dairy products; Antibiotics; Optical filters; Fluorescence; Microfluidics; Light emitting diodes; Frequency modulation; biosensors; dairy products; amplifiers; bio-MEMS; CAPILLARY-ELECTROPHORESIS; FLUORESCENCE DETECTION; ANTIBIOTIC-RESIDUES; SENSITIVITY; OPTIMIZATION; FABRICATION; INJECTION; SODIUM; ARRAY; BIAS;
D O I：
10.1109/ACCESS.2023.3270136
中图分类号：
TP [自动化技术、计算机技术];
学科分类号：
0812 ;
摘要：
This work introduces a sensor for dairy antibiotic detection of ciprofloxacin in milk. We provide an important tool for antibiotic detection in milk and the main contributions of this work are as follows. We introduce a technique based on florescence spectroscopy and lock-in amplification for sensing ciprofloxacin in milk that is capable of detection below the regulatory limit. We compare the system against one without the integrated lock-in amplification, as in traditional fluorescence sensors. We provide microchip capillary electrophoresis results and place our work in context for future integration with microchip capillary electrophoresis.
引用
收藏
页码：41697 / 41707
页数：11
相关论文
共 71 条
[1]   Electroosmotic flow: From microfluidics to nanofluidics [J].
Alizadeh, Amer ;
Hsu, Wei-Lun ;
Wang, Moran ;
Daiguji, Hirofumi .
ELECTROPHORESIS, 2021, 42 (7-8) :834-868
[2]   Fluorescent carbon nanodots as efficient nitro aromatic sensor-analysis based on computational perspectives [J].
Ansi, V. A. ;
Vijisha, K. R. ;
Muraleedharan, K. ;
Renuka, N. K. .
SENSORS AND ACTUATORS A-PHYSICAL, 2020, 302
[3]   Characterization of platinum and titanium thermistors for terahertz antenna-coupled bolometer applications [J].
Banerjee, Amit ;
Satoh, Hiroaki ;
Sharma, Yash ;
Hiromoto, Norihisa ;
Inokawa, Hiroshi .
SENSORS AND ACTUATORS A-PHYSICAL, 2018, 273 :49-57
[4]   Concentration dependence of fluorescence signal in a microfluidic fluorescence detector [J].
Banerjee, Ansuman ;
Shuai, Yun ;
Dixit, Rahul ;
Papautsky, Ian ;
Klotzkin, David .
JOURNAL OF LUMINESCENCE, 2010, 130 (06) :1095-1100
[5]   Fabrication and Characterization of Fully Integrated Microfluidic Device With Carbon Sensing Electrode for the Analysis of Selected Biomedical Targets [J].
Bani-Yaseen, Abdulilah A. Dawoud .
IEEE SENSORS JOURNAL, 2009, 9 (1-2) :81-86
[6]   Evaluation of the Charm maximum residue limit β-lactam and tetracycline test for the detection of antibiotics in ewe and goat milk [J].
Beltran, M. C. ;
Romero, T. ;
Althaus, R. L. ;
Molina, M. P. .
JOURNAL OF DAIRY SCIENCE, 2013, 96 (05) :2737-2745
[7]   Application of Capillary Electrophoresis with Laser-Induced Fluorescence to Immunoassays and Enzyme Assays [J].
Binh Thanh Nguyen ;
Kang, Min-Jung .
MOLECULES, 2019, 24 (10)
[8]   Analysis of 27 antibiotic residues in raw cow's milk and milk-based products validation of Delvotest® T [J].
Bion, Cindy ;
Henzelin, Andrea Beck ;
Qu, Yajuan ;
Pizzocri, Giuseppe ;
Bolzoni, Giuseppe ;
Buffoli, Elena .
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 2016, 33 (01) :54-59
[9]   Ultrafast Charge-Carrier Dynamics of Copper Oxide Nanocrystals [J].
Born, Brandon ;
Krupa, Jeffrey D. A. ;
Geoffroy-Gagnon, Simon ;
Hristovski, Ilija R. ;
Collier, Christopher M. ;
Holzman, Jonathan F. .
ACS PHOTONICS, 2016, 3 (12) :2475-2481
[10]   Ultrafast All-Optical Switching via Subdiffractional Photonic Nanojets and Select Semiconductor Nanoparticles [J].
Born, Brandon ;
Geoffroy-Gagnon, Simon ;
Krupa, Jeffrey D. A. ;
Hristoyski, Ilija R. ;
Collier, Christopher M. ;
Holzman, Jonathan F. .
ACS PHOTONICS, 2016, 3 (06) :1095-1101
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